Physiology of astroglia

A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

Toxic effects of glyphosate on the nervous system: a systematic review

C Costas-Ferreira, R Durán, LRF Faro - International journal of molecular …, 2022 - mdpi.com
Glyphosate, a non-selective systemic biocide with broad-spectrum activity, is the most widely
used herbicide in the world. It can persist in the environment for days or months, and its …

The link between neuroinflammation and the neurovascular unit in synucleinopathies

Q Wang, J Zheng, S Pettersson, R Reynolds… - Science advances, 2023 - science.org
The neurovascular unit (NVU) is composed of vascular cells, glial cells, and neurons. As a
fundamental functional module in the central nervous system, the NVU maintains …

Chronic stress followed by social isolation promotes depressive-like behaviour, alters microglial and astrocyte biology and reduces hippocampal neurogenesis in …

A Du Preez, D Onorato, I Eiben, K Musaelyan… - Brain, behavior, and …, 2021 - Elsevier
Unpredictable chronic mild stress (UCMS) is one of the most commonly used, robust and
translatable models for studying the neurobiological basis of major depression. Although the …

The S100B story: from biomarker to active factor in neural injury

F Michetti, N D'Ambrosi, A Toesca… - Journal of …, 2019 - Wiley Online Library
S100B is a Ca2+‐binding protein mainly concentrated in astrocytes. Its levels in biological
fluids (cerebrospinal fluid, peripheral and cord blood, urine, saliva, amniotic fluid) are …

Functions of S100 proteins

R Donato, BR cannon, G Sorci, F Riuzzi… - Current molecular …, 2013 - ingentaconnect.com
The S100 protein family consists of 24 members functionally distributed into three main
subgroups: those that only exert intracellular regulatory effects, those with intracellular and …

Targeting the receptor for advanced glycation endproducts (RAGE): a medicinal chemistry perspective

S Bongarzone, V Savickas, F Luzi… - Journal of medicinal …, 2017 - ACS Publications
The receptor for advanced glycation endproducts (RAGE) is an ubiquitous, transmembrane,
immunoglobulin-like receptor that exists in multiple isoforms and binds to a diverse range of …

S100B, actor and biomarker of mild traumatic brain injury

C Oris, S Kahouadji, J Durif, D Bouvier… - International Journal of …, 2023 - mdpi.com
Mild traumatic brain injury (mTBI) accounts for approximately 80% of all TBI cases and is a
growing source of morbidity and mortality worldwide. To improve the management of …

Alzheimer's disease pathogenesis: Role of autophagy and mitophagy focusing in microglia

M Eshraghi, A Adlimoghaddam… - International Journal of …, 2021 - mdpi.com
Alzheimer's disease (AD) is a debilitating neurological disorder, and currently, there is no
cure for it. Several pathologic alterations have been described in the brain of AD patients …

Cellular signalling of the receptor for advanced glycation end products (RAGE)

J Xie, JD Méndez, V Méndez-Valenzuela… - Cellular signalling, 2013 - Elsevier
The receptor for advanced glycation end-product (RAGE) is the signal transduction receptor
which senses a variety of signalling molecules including advanced glycation end products …