Understanding the Influence of API Conformations on Amorphous Dispersion Formation Potential Predictions using the R3m Molecular Descriptor

K DeBoyace, M Bookwala, D Zhou… - Molecular …, 2024 - ACS Publications
The R 3 m molecular descriptor (R-GETAWAY third-order autocorrelation index weighted by
the atomic mass) has previously been shown to encode molecular attributes that appear to …

Metal free regioselective synthesis, crystal structure, antioxidant evaluation and Hirshfeld surface analysis of 4, 5-diaryl isoxazoles

R Kumar, R Kamal, V Kumar, P Chetti - Journal of Molecular Structure, 2023 - Elsevier
The current work describes the synthetic utilization of different α-aryl-β, β-ditosyloxy ketones
as 1, 3-dielectrophilic three carbon intermediates for the synthesis of scarcely under …

[PDF][PDF] Crystal structure of 4-bromo-N-(propylcarbamoyl) benzenesulfonamide

M Bookwala, S Patel, PT Flaherty… - Acta Crystallographica …, 2022 - journals.iucr.org
The title compound, C10H13BrN2O3S, 1, contains a sulfonyl urea moiety, which possesses
potential therapeutic functions (eg, anti-diabetic and herbicidal). The geometry of 1 is similar …

Uncovering the mechanism of action of cardiac arrhythmias caused by cancer therapeutics that target the hERG channel: A Literature review

R Finger - 2022 - studenttheses.uu.nl
Over the years, tremendous progression in development of cancer treatments has taken
place with more cancer survivors as a result. As more cancer-survivors live with the long …