[HTML][HTML] Stimuli-responsive nanocarriers for drug delivery, tumor imaging, therapy and theranostics

P Mi - Theranostics, 2020 - ncbi.nlm.nih.gov
In recent years, much progress has been motivated in stimuli-responsive nanocarriers,
which could response to the intrinsic physicochemical and pathological factors in diseased …

Nanocarrier cancer therapeutics with functional stimuli-responsive mechanisms

N Kaushik, SB Borkar, SK Nandanwar… - Journal of …, 2022 - Springer
Presently, nanocarriers (NCs) have gained huge attention for their structural ability, good
biocompatibility, and biodegradability. The development of effective NCs with stimuli …

Ultrasound-responsive polymer-based drug delivery systems

P Wei, EJ Cornel, J Du - Drug delivery and translational research, 2021 - Springer
Ultrasound-responsive polymeric materials have received a tremendous amount of attention
from scientists for several decades. Compared to other stimuli-responsive materials (such as …

Recent progress in functionalized and targeted polymersomes and chimeric polymeric nanotheranostic platforms for cancer therapy

M Beygi, F Oroojalian, SS Hosseini… - Progress in Materials …, 2023 - Elsevier
The majority of advances in cancer therapy have been achieved based on developments in
public awareness, as well as novel diagnostic and therapeutic modalities. Treatment …

Exosome as a delivery vehicle for cancer therapy

B Moon, S Chang - Cells, 2022 - mdpi.com
Exosomes are small extracellular vesicles that are naturally produced and carry
biomolecules such as proteins, microRNAs, and metabolites. Because of their small size …

Overcoming hurdles in nanoparticle clinical translation: The influence of experimental design and surface modification

JW Shreffler, JE Pullan, KM Dailey, S Mallik… - International journal of …, 2019 - mdpi.com
Nanoparticles are becoming an increasingly popular tool for biomedical imaging and drug
delivery. While the prevalence of nanoparticle drug-delivery systems reported in the …

Polymersome Membrane Engineering with Active Targeting or Controlled Permeability for Responsive Drug Delivery

A Kayani, A Raza, J Si, D Dutta, Q Zhou… - Biomacromolecules, 2023 - ACS Publications
Polymersomes have been extensively investigated for drug delivery as nanocarriers for two
decades due to a series of advantages including high stability under physiological …

Hypoxia-responsive nanoparticles for tumor-targeted drug delivery

Y Li, J Jeon, JH Park - Cancer Letters, 2020 - Elsevier
Hypoxia is a negative prognostic indicator of solid tumors. Increasing evidence indicates that
the intratumoral hypoxic microenvironment is strongly related to enhanced tumor …

Advancements in polymeric nanocarriers to mediate targeted therapy against triple-negative breast cancer

M Fatima, A Sheikh, MAS Abourehab, P Kesharwani - Pharmaceutics, 2022 - mdpi.com
Triple-negative breast cancer (TNBC) is a destructive disease with a poor prognosis, low
survival rate and high rate of metastasis. It comprises 15% of total breast cancers and is …

Targeting the tumor core: hypoxia-responsive nanoparticles for the delivery of chemotherapy to pancreatic tumors

MI Confeld, B Mamnoon, L Feng… - Molecular …, 2020 - ACS Publications
In pancreatic ductal adenocarcinoma (PDAC), early onset of hypoxia triggers remodeling of
the extracellular matrix, epithelial-to-mesenchymal transition, increased cell survival, the …