Near-infrared fluorescent probes as imaging and theranostic modalities for amyloid-beta and tau aggregates in Alzheimer's disease

H Rai, S Gupta, S Kumar, J Yang… - Journal of Medicinal …, 2022 - ACS Publications
A person suspected of having Alzheimer's disease (AD) is clinically diagnosed for the
presence of principal biomarkers, especially misfolded amyloid-beta (Aβ) and tau proteins in …

A closer look at amyloid ligands, and what they tell us about protein aggregates

TS Chisholm, CA Hunter - Chemical Society Reviews, 2024 - pubs.rsc.org
The accumulation of amyloid fibrils is characteristic of neurodegenerative diseases such as
Alzheimer's disease (AD) and Parkinson's disease. Detecting these fibrils with fluorescent or …

Shedding light on tau protein aggregation: the progress in developing highly selective fluorophores

P Verwilst, HS Kim, S Kim, C Kang… - Chemical Society Reviews, 2018 - pubs.rsc.org
Historically, in Alzheimer's disease research, a lot of attention has been paid to the
development of highly selective fluorophores for beta amyloid plaques. With a shift in the …

Fluorescent probe for selective imaging of α-synuclein fibrils in living cells

P Gaur, M Galkin, A Kurochka, S Ghosh… - ACS Chemical …, 2021 - ACS Publications
Plaques of amyloid fibrils composed of neuronal protein α-synuclein are one of the
hallmarks of Parkinson's disease, and their selective imaging is crucial to study the …

Development of peroxynitrite-responsive fluorescence probe for recognition of drug-induced liver injury

BD Wang, R Wei, MJ Gao, YH Wang, CF Zhang… - … Acta Part A: Molecular …, 2022 - Elsevier
Peroxynitrite (ONOO−) as an active substance, is produced during normal physiological
process, which plays an important role in maintaining cell REDOX balance and cell function …

A colorimetric and ratiometric fluorescent probe for distinguishing cysteine from biothiols in water and living cells

Q Han, Z Shi, X Tang, L Yang, Z Mou, J Li… - Organic & …, 2014 - pubs.rsc.org
A merocyanine-based highly selective colorimetric and ratiometric fluorescent probe is
described for Cys detection in water and diluted deproteinized human serum. Upon reaction …

Organelle-selective near-infrared fluorescent probes for intracellular microenvironment labeling

A Kurutos, Y Shindo, Y Hiruta, K Oka, D Citterio - Dyes and Pigments, 2022 - Elsevier
The design, synthesis, and bio-applicability of a series of 8 near-infrared (NIR) molecular
probes with tunable hydrophilic/hydrophobic properties are described in this paper. The title …

Design, Synthesis, and Characterization of Novel Styryl Dyes as Fluorescent Probes for Tau Aggregate Detection in Vitro and in Cells

W Sangsuwan, K Faikhruea… - Chemistry–An Asian …, 2024 - Wiley Online Library
A series of novel styryl dye derivatives incorporating indolium and quinolinium core
structures were successfully synthesized to explore their interacting and binding capabilities …

A Novel Fluorescent Probe for the Detection of Cyanide Ions in Solutions and Studies on Its Biophysical Interactions with ctDNA and Proteases

B Doyuran, E Gökoğlu, A Zouitini, E Keleş… - Journal of …, 2022 - Springer
A new cationic indolium based styryl dye (Ci) as a fluorescent probe was synthesized and its
anions selectivity/sensitivity properties/molecular interactions with protease enzymes …

Vapochromism of indolenine-based heptamethine cyanine dye adsorbed on silica gel

M Shibayama, Y Uehashi, S Ajioka, Y Kubota… - New Journal of …, 2023 - pubs.rsc.org
Vapochromism of indolenine-based heptamethine cyanine dye adsorbed on silica gel - New
Journal of Chemistry (RSC Publishing) DOI:10.1039/D3NJ00060E Royal Society of Chemistry …