[HTML][HTML] Ureases: Historical aspects, catalytic, and non-catalytic properties–A review

K Kappaun, AR Piovesan, CR Carlini… - Journal of advanced …, 2018 - Elsevier
Abstract Urease (urea amidohydrolase, EC 3.5. 1.5) is a nickel-containing enzyme produced
by plants, fungi, and bacteria that catalyzes the hydrolysis of urea into ammonia and …

[HTML][HTML] Schiff bases and their metal complexes as urease inhibitors–a brief review

 de Fátima, C de Paula Pereira… - Journal of advanced …, 2018 - Elsevier
Schiff bases, an aldehyde-or ketone-like compounds in which the carbonyl group is
replaced by an imine or azomethine, are some of the most widely used organic compounds …

A DNAzyme‐Based Colorimetric Paper Sensor for Helicobacter pylori

MM Ali, M Wolfe, K Tram, J Gu, CDM Filipe… - Angewandte …, 2019 - Wiley Online Library
The reliable detection of pathogenic bacteria in complex biological samples using simple
assays or devices remains a major challenge. Herein, we report a simple colorimetric paper …

Plant toxic proteins: their biological activities, mechanism of action and removal strategies

E Kocyigit, B Kocaadam-Bozkurt, O Bozkurt… - Toxins, 2023 - mdpi.com
Plants evolve to synthesize various natural metabolites to protect themselves against
threats, such as insects, predators, microorganisms, and environmental conditions (such as …

Soil urease inhibition by various plant extracts

MA Rana, R Mahmood, S Ali - Plos one, 2021 - journals.plos.org
Urea is the most popular and widely used nitrogenous fertilizer. High soil urease activity
rapidly hydrolyses applied urea to ammonia which contributes to soil nitrogen (N) losses …

[HTML][HTML] Damaged myofiber-derived metabolic enzymes act as activators of muscle satellite cells

Y Tsuchiya, Y Kitajima, H Masumoto, Y Ono - Stem cell reports, 2020 - cell.com
Muscle satellite cells are normally quiescent but are rapidly activated following muscle
damage. Here, we investigated whether damaged myofibers influence the activation of …

Design and synthesis of novel anti-urease imidazothiazole derivatives with promising antibacterial activity against Helicobacter pylori

AI Shahin, S Zaib, SO Zaraei, RA Kedia, HS Anbar… - PLoS …, 2023 - journals.plos.org
Urease enzyme is a known therapeutic drug target for treatment of Helicobacter pylori
infection due to its role in settlement and growth in gastric mucosa. In this study, we …

Developing hybrid molecule therapeutics for diverse enzyme inhibitory action: Active role of coumarin-based structural leads in drug discovery

A Ibrar, SA Shehzadi, F Saeed, I Khan - Bioorganic & Medicinal Chemistry, 2018 - Elsevier
Hybrid drugs featuring two or more potentially bioactive pharmacophores have been
recognized as advanced and superior chemical entities to simultaneously modulate multiple …

Genomics of urea transport and catabolism in cyanobacteria: biotechnological implications

T Veaudor, C Cassier-Chauvat, F Chauvat - Frontiers in microbiology, 2019 - frontiersin.org
Cyanobacteria are widely-diverse prokaryotes that colonize our planet. They use solar
energy to assimilate huge amounts of atmospheric CO2 and produce a large part of the …

Helicobacter pylori Urease: Potential Contributions to Alzheimer's Disease

AF Uberti, N Callai-Silva, MVC Grahl… - International journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) causes dementia and memory loss in the elderly. Deposits of beta-
amyloid peptide and hyperphosphorylated tau protein are present in a brain with AD. A …