The diagnosis and treatment of neurological ailments always remain an utmost challenge for
research fraternity due to the presence of BBB. The intranasal route appeared as an …

Abstract Poloxamer 407 copolymer (ethylene oxide and propylene oxide blocks) shows
thermoreversible properties, which is of the utmost interest in optimising drug formulation …

Thermoresponsive gels containing gold nanoparticles (AuNPs) were prepared using
Pluronic® 127 alone (F1) and with hydroxypropyl methylcellulose (F2) at ratios of 15% w/w …

The process of mucoadhesion involving a polymeric drug delivery platform is a complex one
that includes wetting, adsorption and interpenetration of polymer chains amongst various …

Pluronics are amphiphilic triblock copolymers composed of two hydrophilic poly (ethylene
oxide)(PEO) chains linked via a central hydrophobic polypropylene oxide (PPO). Owing to …

Context: In recent years, nanotechnology-based delivery systems have gained interest to
overcome the problems of restricted absorption of therapeutic agents from the nasal cavity …

In order to cure and treat health-related disorders, therapeutic substance must reach its
target site with a constant concentration over a long period of time. As oral administration is …

The prolonged residence of drug formulation in the nasal cavity is of utmost importance for
intranasal drug delivery. The objective of the present investigation was to develop a …

The purpose of the present study was to develop intranasal delivery systems of sumatriptan
using thermoreversible polymer Pluronic F127 (PF 127) and mucoadhesive polymer …

Donepezil (DPZ) is widely used in the treatment of Alzheimer's disease in tablet form for oral
administration. The pharmacological efficacy of this drug can be enhanced by the use of …