Inflammation in chronic wounds

R Zhao, H Liang, E Clarke, C Jackson… - International journal of …, 2016 - mdpi.com
Non-healing chronic wounds present a major biological, psychological, social, and financial
burden on both individual patients and the broader health system. Pathologically extensive …

Wound chronicity, impaired immunity and infection in diabetic patients

N Rodríguez-Rodríguez, I Martínez-Jiménez… - MEDICC …, 2022 - SciELO Public Health
BACKGROUND Diabetic foot ulcers are a common diabetic complication leading to
alarming figures of amputation, disability, and early mortality. The diabetic glucooxidative …

A multifunctional pro‐healing zwitterionic hydrogel for simultaneous optical monitoring of pH and glucose in diabetic wound treatment

Y Zhu, J Zhang, J Song, J Yang, Z Du… - Advanced Functional …, 2020 - Wiley Online Library
Diabetic ulcer is the most common kind of chronic wound worldwide. Though great efforts
have been devoted, diabetic ulcer still remains as a challenge that requires constant …

GMSC-derived exosomes combined with a chitosan/silk hydrogel sponge accelerates wound healing in a diabetic rat skin defect model

Q Shi, Z Qian, D Liu, J Sun, X Wang, H Liu, J Xu… - Frontiers in …, 2017 - frontiersin.org
Background: Delayed wound healing in diabetic patients is one of the most challenging
complications in clinical medicine, as it poses a greater risk of gangrene, amputation and …

Smart battery-free and wireless bioelectronic platform based on a nature-skin-derived organohydrogel for chronic wound diagnosis, assessment, and accelerated …

Z Bai, X Wang, M Huang, Y Feng, S Sun, M Zheng… - Nano Energy, 2023 - Elsevier
Using smart electroactive hydrogels with emerging bioelectronics to monitor wound status
wirelessly in real-time is a promising approach as an unremitting therapy for refractory …

Updates in diabetic wound healing, inflammation, and scarring

N Dasari, A Jiang, A Skochdopole… - Seminars in plastic …, 2021 - thieme-connect.com
Diabetic patients can sustain wounds either as a sequelae of their disease process or
postoperatively. Wound healing is a complex process that proceeds through phases of …

Poly-quercetin-based nanoVelcro as a multifunctional wound dressing for effective treatment of chronic wound infections

YJ Li, SC Wei, HW Chu, HJ Jian, A Anand… - Chemical Engineering …, 2022 - Elsevier
Comprehensive wound dressings for bacterial wound treatment requires a combination of
antibacterial, antioxidative, and anti-inflammatory effects and endotoxin neutralization. Here …

Mesenchymal stem cells adaptively respond to environmental cues thereby improving granulation tissue formation and wound healing

D Jiang, K Scharffetter-Kochanek - Frontiers in cell and …, 2020 - frontiersin.org
Granulation tissue formation constitutes a key step during wound healing of the skin and
other organs. Granulation tissue concomitantly initiates regenerative M2 macrophages …

Efficacy of comprehensive ozone therapy in diabetic foot ulcer healing

M Izadi, R Kheirjou, R Mohammadpour… - Diabetes & Metabolic …, 2019 - Elsevier
Background Diabetic foot ulcer is one of the common complications of diabetes disease that
is costly and difficult to treat. This problem can lead to morbidity and even mortality. Ozone is …

Hyperglycemia acts in synergy with hypoxia to maintain the pro-inflammatory phenotype of macrophages

M Morey, P O'Gaora, A Pandit, C Hélary - PloS one, 2019 - journals.plos.org
Diabetic foot ulcers (DFUs) are characterized by a chronic inflammation state which prevents
cutaneous wound healing, and DFUs eventually lead to infection and leg amputation …