Viewing metabolism through the lens of exercise biology has proven an accessible and
practical strategy to gain new insights into local and systemic metabolic regulation. Recent …

Highlights•H3K4 monomethylation (H3K4me1) is a conserved histone mark.•H3K4me1 is
implicated in various regulatory stages of gene regulation.•Data supporting and opposing a …

Skeletal muscle fibers express distinct gene programs during development and maturation,
but the underlying gene regulatory networks that confer stage-specific myofiber properties …

Physiology is regulated by interconnected cell and tissue circadian clocks. Disruption of the
rhythms generated by the concerted activity of these clocks is associated with metabolic …

Skeletal muscle is a pivotal organ in humans that maintains locomotion and homeostasis.
Muscle atrophy caused by sarcopenia and cachexia, which results in reduced muscle mass …

Background Disuse atrophy is a frequent cause of muscle atrophy, which can occur in
individuals of any age who have been inactive for a prolonged period or immobilization …

Skeletal muscle is the most abundant component of the mature mammalian phenotype.
Designed to generate contractile force and movement, skeletal muscle is crucial for …

Skeletal muscle is sensitive to gravitational alterations. We recently developed a multiple
artificial-gravity research system (MARS), which can generate gravity ranging from …

Despite advancements in treatment, approximately 25% of patients with breast cancer
experience long-term skeletal muscle wasting (SMW), which limits mobility, reduces drug …

The skeletal muscle fiber profile is closely related to livestock meat quality. However, the
molecular mechanisms determining muscle fiber types in donkeys are not completely …