Immunological dimensions of neuroinflammation and microglial activation: exploring innovative immunomodulatory approaches to mitigate neuroinflammatory …

L Fornari Laurindo, J Aparecido Dias… - Frontiers in …, 2024 - frontiersin.org
The increasing life expectancy has led to a higher incidence of age-related
neurodegenerative conditions. Within this framework, neuroinflammation emerges as a …

NRF2, a crucial modulator of skin cells protection against vitiligo, psoriasis, and cancer

E Panieri, P Telkoparan‐Akillilar, L Saso - BioFactors, 2023 - Wiley Online Library
The skin represents a physical barrier between the organism and the environment that has
evolved to confer protection against biological, chemical, and physical insults. The inner …

Rutin Protects fibroblasts from UVA radiation through stimulation of Nrf2 pathway

E Tabolacci, G Tringali, V Nobile, S Duca… - Antioxidants, 2023 - mdpi.com
This study explores the photoprotective effects of rutin, a bioflavonoid found in some
vegetables and fruits, against UVA-induced damage in human skin fibroblasts. Our results …

In vitro, ex vivo, and clinical evaluation of anti‐aging gel containing EPA and CBD

G Cohen, J Jakus, M Portillo, R Gvirtz… - Journal of Cosmetic …, 2023 - Wiley Online Library
Background Skin aging manifestation, such as coarse wrinkles, loss of elasticity,
pigmentation, and rough‐textured appearance, is a multifactorial process that can be …

Obacunone Photoprotective Effects against Solar-Simulated Radiation–Induced Molecular Modifications in Primary Keratinocytes and Full-Thickness Human Skin

P Montero, MJ Villarroel, I Roger, A Morell… - International Journal of …, 2023 - mdpi.com
Solar radiation can cause damage to the skin, leading to various adverse effects such as
sunburn, reactive oxygen species production, inflammation, DNA damage, and photoaging …

Clinical Applications of Polypodium leucotomos (Fernblock®): An Update

A Rodríguez-Luna, A Zamarrón, Á Juarranz… - Life, 2023 - mdpi.com
Exposure to sun radiation leads to higher risk of sunburn, pigmentation,
immunosuppression, photoaging and skin cancer. In addition to ultraviolet radiation (UVR) …

[HTML][HTML] Targeting oncogenic transcription factors in skin malignancies: An update on cancer stemness and therapeutic outcomes

M Steinhoff, M Alam, A Ahmad, S Uddin… - Seminars in Cancer …, 2022 - Elsevier
The skin is the largest organ of the human body and prone to various diseases, including
cancer; thus, provides the first line of defense against exogenous biological and non …

Electrospun Multifunctional Radiation Shielding Nanofibrous Membrane for Daily Human Protection

P Chen, L Wang, M Liao, Z Liu, H Zhao… - Advanced Materials …, 2023 - Wiley Online Library
With the widespread utilization of many radiation instruments, people are inadvertently
suffering from radiation damage. But nowadays, there is still a lack of a lightweight …

The skin photoprotective effect of trilinolein: Induction of cellular autophagy via the AMPK-mTOR signaling pathway

X Lin, N Deng, H Li, J Duan, W Chen, T Liu… - Toxicology and Applied …, 2024 - Elsevier
Trilinolein (TL) is an active substance contained in traditional Chinese herbs; modern
studies have shown that trilinolein has anti-inflammatory and antioxidant effects on the body …

Possible involvement of dermal fibroblasts in modulating Nrf2 signaling in epidermal keratinocytes

Y Tsuruta, Y Katsuyama, Y Okano, T Ozawa… - Biological and …, 2023 - jstage.jst.go.jp
Epidermal keratinocytes protect themselves by cooperating with neighboring cells against
internal and external stresses, which leads not only to the maintenance of cell homeostasis …