IntelliCage: the development and perspectives of a mouse-and user-friendly automated behavioral test system
HP Lipp, S Krackow, E Turkes, S Benner… - Frontiers in Behavioral …, 2024 - frontiersin.org
IntelliCage for mice is a rodent home-cage equipped with four corner structures harboring
symmetrical double panels for operant conditioning at each of the two sides, either by …
symmetrical double panels for operant conditioning at each of the two sides, either by …
[HTML][HTML] Factors predisposing to humoral autoimmunity against brain-antigens in health and disease: Analysis of 49 autoantibodies in over 7000 subjects
VD Gastaldi, JBH Wilke, CA Weidinger, C Walter… - Brain, Behavior, and …, 2023 - Elsevier
Background Circulating autoantibodies (AB) against brain-antigens, often deemed
pathological, receive increasing attention. We assessed predispositions and …
pathological, receive increasing attention. We assessed predispositions and …
Impaired functional connectivity of the hippocampus in translational murine models of NMDA-receptor antibody associated neuropsychiatric pathology
J Kuchling, B Jurek, M Kents, J Kreye, C Geis… - Molecular …, 2024 - nature.com
Decreased hippocampal connectivity and disruption of functional networks are established
resting-state functional MRI (rs-fMRI) features that are associated with neuropsychiatric …
resting-state functional MRI (rs-fMRI) features that are associated with neuropsychiatric …
[HTML][HTML] HSV-1 and cellular miRNAs in CSF-derived exosomes as diagnostically relevant biomarkers for neuroinflammation
C Scheiber, HC Klein, JM Schneider, T Schulz… - Cells, 2024 - mdpi.com
Virus-associated chronic inflammation may contribute to autoimmunity in a number of
diseases. In the brain, autoimmune encephalitis appears related to fluctuating reactivation …
diseases. In the brain, autoimmune encephalitis appears related to fluctuating reactivation …
[HTML][HTML] NMDAR autoantibodies in psychiatric disease-an immunopsychiatric continuum and potential predisposition for disease pathogenesis
N Hansen - Journal of Translational Autoimmunity, 2022 - Elsevier
Abstract N-Methyl-d-Aspartate-receptor (NMDAR) antibody encephalitis is a disease
discovered two decades ago. Our knowledge about it has recently deepened dramatically …
discovered two decades ago. Our knowledge about it has recently deepened dramatically …
NMDAR1 autoantibodies amplify behavioral phenotypes of genetic white matter inflammation: a mild encephalitis model with neuropsychiatric relevance
S Arinrad, JBH Wilke, A Seelbach, J Doeren… - Molecular …, 2022 - nature.com
Encephalitis has an estimated prevalence of≤ 0.01%. Even with extensive diagnostic work-
up, an infectious etiology is identified or suspected in< 50% of cases, suggesting a role for …
up, an infectious etiology is identified or suspected in< 50% of cases, suggesting a role for …
Intestinal dysbiosis exacerbates susceptibility to the anti-NMDA receptor encephalitis-like phenotype by changing blood brain barrier permeability and immune …
X Gong, Y Ma, X Deng, A Li, X Li, X Kong, Y Liu… - Brain, Behavior, and …, 2024 - Elsevier
Abstract Changes in the intestinal microbiota have been observed in patients with anti-N-
methyl-D-aspartate receptor encephalitis (NMDARE). However, whether and how the …
methyl-D-aspartate receptor encephalitis (NMDARE). However, whether and how the …
A peptide from the Japanese encephalitis virus failed to induce the production of anti-N-methyl-d-aspartate receptor antibodies via molecular mimicry in mice
H Luo, J Yang, X Yang, Z Han, Z Fang, D Huang, J Gui… - Heliyon, 2024 - cell.com
Background The development of anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis
following viral encephalitis, such as Japanese encephalitis, has received increasing …
following viral encephalitis, such as Japanese encephalitis, has received increasing …
[HTML][HTML] Peptide-purified anti-N-methyl-D-aspartate Receptor (NMDAR) autoantibodies have inhibitory effect on long-term synaptic plasticity
C Day, JP Silva, R Munro, B Mullier, VM André, C Wolff… - Pharmaceuticals, 2024 - mdpi.com
Background/Objectives: Recent studies, typically using patient cerebrospinal fluid (CSF),
have suggested that different autoantibodies (Aabs) acting on their respective receptors …
have suggested that different autoantibodies (Aabs) acting on their respective receptors …
Аутоиммунный анти-NMDA-энцефалит, ассоциированный с новой коронавирусной инфекцией COVID-19
НИ Панченко, НВ Шулешова, ДИ Руденко… - Российский …, 2023 - rnj.com
Аннотация В статье представлен клинический случай 19-летней пациентки с
достоверным аутоиммунным анти-NMDА-энцефалитом на фоне перенесенной …
достоверным аутоиммунным анти-NMDА-энцефалитом на фоне перенесенной …