Prostate Cancer Morphologies: Cribriform Pattern and Intraductal Carcinoma Relations to Adverse Pathological and Clinical Outcomes—Systematic Review and Meta …

R Osiecki, M Kozikowski, B Sarecka-Hujar, M Pyzlak… - Cancers, 2023 - mdpi.com
Simple Summary Prostate cancer is one of the most common male cancers. A more accurate
disease assessment is needed to better stratify patients' risks and guide treatment decisions …

Intraductal carcinoma of the prostate as a cause of prostate cancer metastasis: a molecular portrait

H Pantazopoulos, MK Diop, AA Grosset… - Cancers, 2022 - mdpi.com
Simple Summary Most men with prostate cancer will live as long as those who do not have
prostate cancer. However, some men will die early of their disease due to a particular type of …

Genetic and epigenetic determinants of aggressiveness in cribriform carcinoma of the prostate

H Elfandy, J Armenia, F Pederzoli, E Pullman… - Molecular Cancer …, 2019 - AACR
Among prostate cancers containing Gleason pattern 4, cribriform morphology is associated
with unfavorable clinicopathologic factors, but its genetic features and association with long …

Somatic driver mutation prevalence in 1844 prostate cancers identifies ZNRF3 loss as a predictor of metastatic relapse

M Fraser, J Livingstone, JL Wrana, A Finelli… - Nature …, 2021 - nature.com
Driver gene mutations that are more prevalent in metastatic, castration-resistant prostate
cancer (mCRPC) than localized disease represent candidate prognostic biomarkers. We …

Cribriform prostate cancer: clinical pathologic and molecular considerations

AB Hesterberg, JB Gordetsky, PJ Hurley - Urology, 2021 - Elsevier
Intraductal cribriform (IDC) and invasive cribriform morphologies are associated with worse
prostate cancer outcomes. Limited retrospective studies have associated IDC and cribriform …

Cribriform patterned lesions in the prostate gland with emphasis on differential diagnosis and clinical significance

M Destouni, AC Lazaris, V Tzelepi - Cancers, 2022 - mdpi.com
Simple Summary A cribriform structure is defined as a continuous proliferation of cells with
intermingled lumina. Various entities may have a cribriform morphology within the prostate …

Transcriptomic heterogeneity of expansile cribriform and other Gleason Pattern 4 prostate cancer subtypes

MR Chappidi, M Sjöström, NY Greenland… - European Urology …, 2024 - Elsevier
Background Prostate cancers featuring an expansile cribriform (EC) pattern are associated
with worse clinical outcomes following radical prostatectomy (RP). However, studies of the …

Prostate cancer with cribriform morphology: diagnosis, aggressiveness, molecular pathology and possible relationships with intraductal carcinoma

R Montironi, A Cimadamore, S Gasparrini… - Expert Review of …, 2018 - Taylor & Francis
ABSTRACT Introduction: The Gleason grading system is one of the most important
prognostic factors in prostate cancer (PCa). From the 2005 to the 2014 conference …

Historical and contemporary perspectives on cribriform morphology in prostate cancer

M Truong, T Frye, E Messing, H Miyamoto - Nature Reviews Urology, 2018 - nature.com
The Gleason scoring system is widely used for the grading and prognostication of prostate
cancer. A Gleason pattern 4 subtype known as cribriform morphology has now been …

Intraductal carcinoma of the prostate: pathogenesis and molecular perspectives

Y Zong, R Montironi, F Massari, Z Jiang… - European Urology …, 2021 - Elsevier
Intraductal carcinoma of the prostate (IDC-P), a clinicopathological entity characterized by
malignant prostatic epithelial cells growing within ducts and/or acini, has a distinct …