Synthesis and pharmacological activities of pyrazole derivatives: A review

K Karrouchi, S Radi, Y Ramli, J Taoufik, YN Mabkhot… - Molecules, 2018 - mdpi.com
Pyrazole and its derivatives are considered a pharmacologically important active scaffold
that possesses almost all types of pharmacological activities. The presence of this nucleus in …

Pyridine compounds with antimicrobial and antiviral activities

M Marinescu, CV Popa - International journal of molecular sciences, 2022 - mdpi.com
In the context of the new life-threatening COVID-19 pandemic caused by the SARS-CoV-2
virus, finding new antiviral and antimicrobial compounds is a priority in current research …

Synthesis, molecular docking and antimicrobial activity of new fused pyrimidine and pyridine derivatives

MAA Radwan, MA Alshubramy, M Abdel-Motaal… - Bioorganic …, 2020 - Elsevier
Synthesis of some new heterocyclic ring systems incorporated pyrimidine and pyridine
moieties starting from 1-(furan-2-yl)-3-(thiophen-2-yl) chalcone was achieved. The structure …

Design and synthesis of isoniazid-based pyrazolines as potential inhibitors of Mycobacterium tuberculosis with promising radical scavenging action: in-vitro and in …

J Rasgania, R Gavadia, M Varma-Basil… - Journal of Molecular …, 2024 - Elsevier
In view of the devastating tuberculosis infections and emerging resistance against available
drugs, novel 5-phenyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-pyrazol-1-yl)(pyridin-4-yl) …

Thiophene‐containing compounds with antimicrobial activity

G Roman - Archiv der Pharmazie, 2022 - Wiley Online Library
Thiophene, as a member of the group of five‐membered heterocycles containing one
heteroatom, is one of the simplest heterocyclic systems. Many synthetic strategies allow the …

Thiophene derivatives: A potent multitargeted pharmacological scaffold

A Singh, G Singh, PMS Bedi - Journal of Heterocyclic …, 2020 - Wiley Online Library
Despite a significant work that has been done on thiophene, continuous efforts are still being
made by the researchers to identify novel heterocyclic compounds with potential …

Synthesis, ADMET properties, and in vitro antimicrobial and antibiofilm activity of 5-nitro-2-thiophenecarbaldehyde N-((E)-(5-nitrothienyl) methylidene) hydrazone …

P Kavaliauskas, B Grybaite, V Mickevicius… - Antibiotics, 2020 - mdpi.com
The emergence of drug-resistant Staphylococcus aureus is responsible for high morbidity
and mortality worldwide. New therapeutic options are needed to fight the increasing …

Pyrimido[1,2-a]benzimidazoles: synthesis and perspective of their pharmacological use

VV Fedotov, VL Rusinov, EN Ulomsky… - Chemistry of …, 2021 - Springer
Pyrimido[1,2-a]benzimidazoles: synthesis and perspective of their pharmacological use |
SpringerLink Skip to main content Advertisement SpringerLink Log in Menu Find a journal …

Methods of synthesis for the azolo [1, 2, 4] triazines

EK Voinkov, RA Drokin, EN Ulomsky… - Chemistry of …, 2020 - Springer
The review summarizes and analyzes data from modern information sources on the
methods of synthesis of azolo [X, Yc][1, 2, 4] triazines. Approaches to the construction of the …

Recent advances in 1, 2, 4-triazolo [1, 5-a] pyrimidine chemistry

G Fischer - Advances in Heterocyclic Chemistry, 2019 - Elsevier
The review deals with the pharmaceutically and agrochemically important group of 1, 2, 4-
triazolo [1, 5-a] pyrimidines (TPs) and covers relevant literature published from about 2006 …