Until recently, there were no generalizable methods for assessing the effects of post‐
translational regulation on enzymatic activity. Activity‐based sensing (ABS) has emerged as …

Phosphoglycerate kinase (PGK) is a glycolytic enzyme that is well conserved among the
three domains of life. PGK is usually a monomeric enzyme of about 45 kDa that catalyses …

Abstract Background and methods Multiple Na+/K+-ATPase (NKA) α-subunit isoforms
express differentially in response to salinity transfer in teleosts but we observed that the …

Essentially nothing is known about the molecular underpinnings of crustacean circadian
clocks. The genome of Daphnia pulex, the only crustacean genome available for public use …

Although great effort has been expended to understand cancer's origins, less attention has
been given to the primary cause of cancer deaths—cancer recurrences and their sequelae …

It is well established that tumour cells undergo metabolic changes to acquire biological
advantage over normal cells with activation of the glycolytic pathway, a process termed …

Tolerance of organisms towards heterogeneous and variable environments is highly related
to physiological flexibility. An effective strategy to enhance physiological flexibility is the …

Living systems, whether healthy or diseased, must obey the laws of chemistry. The purpose
of this review is to identify the interpretive limits of cellular biochemistry using, largely, the …

Abstract The Hodgkin-Huxley (HH) model is the basis for numerous neural models. There
are two negative feedback processes in the HH model that regulate rhythmic spiking. The …

Bis vor kurzem gab es keine allgemeinen Methoden zur Abschätzung der Auswirkungen
post‐translationaler Regulierung auf die Enzymaktivität. Aktivitätsbasierte Sensorik (ABS) …