Antimicrobial peptide-based materials: Opportunities and challenges

A Rai, R Ferrão, P Palma, T Patricio… - Journal of Materials …, 2022 - pubs.rsc.org
The multifunctional properties of antimicrobial peptides (AMPs) make them attractive
candidates for the treatment of various diseases. AMPs are considered as alternatives to …

A roadmap to pulmonary delivery strategies for the treatment of infectious lung diseases

S He, J Gui, K Xiong, M Chen, H Gao, Y Fu - Journal of nanobiotechnology, 2022 - Springer
Pulmonary drug delivery is a highly attractive topic for the treatment of infectious lung
diseases. Drug delivery via the pulmonary route offers unique advantages of no first-pass …

Polymeric nano-and microparticulate drug delivery systems for treatment of biofilms

SE Birk, A Boisen, LH Nielsen - Advanced Drug Delivery Reviews, 2021 - Elsevier
Now-a-days healthcare systems face great challenges with antibiotic resistance and low
efficacy of antibiotics when combating pathogenic bacteria and bacterial biofilms …

Progress on the pathological tissue microenvironment barrier-modulated nanomedicine

H Han, L Xing, BT Chen, Y Liu, TJ Zhou, Y Wang… - Advanced Drug Delivery …, 2023 - Elsevier
Imbalance in the tissue microenvironment is the main obstacle to drug delivery and
distribution in the human body. Before penetrating the pathological tissue microenvironment …

Antioxidant biodegradable covalent cyclodextrin frameworks as particulate carriers for inhalation therapy against acute lung injury

S He, L Wu, H Sun, D Wu, C Wang, X Ren… - … Applied Materials & …, 2022 - ACS Publications
Drug therapies for acute lung injury (ALI) are far from satisfactory, primarily because drugs
cannot specifically target the lungs. Direct delivery of drugs to the deep alveolar regions by …

Current advances in lipid and polymeric antimicrobial peptide delivery systems and coatings for the prevention and treatment of bacterial infections

ME van Gent, M Ali, PH Nibbering, SN Kłodzińska - Pharmaceutics, 2021 - mdpi.com
Bacterial infections constitute a threat to public health as antibiotics are becoming less
effective due to the emergence of antimicrobial resistant strains and biofilm and persister …

Application of PLGA as a biodegradable and biocompatible polymer for pulmonary delivery of drugs

R Mahar, A Chakraborty, N Nainwal, R Bahuguna… - Aaps Pharmscitech, 2023 - Springer
Pulmonary administration of biodegradable polymeric formulation is beneficial in the
treatment of various respiratory diseases. For respiratory delivery, the polymer must be non …

Bridging nanoplatform and vaccine delivery, a landscape of strategy to enhance nasal immunity

Z Teng, LY Meng, JK Yang, Z He, XG Chen… - Journal of Controlled …, 2022 - Elsevier
Vaccination is an urgently needed and effective option to address epidemic, cancers,
allergies, and other diseases. Nasal administration of vaccines offers many benefits over …

Microspheres for targeted drug delivery-A review on recent applications

AN Yawalkar, MA Pawar, PR Vavia - Journal of Drug Delivery Science and …, 2022 - Elsevier
Microspheres are one of the most explored drug carriers for site-specific delivery of cargoes
in a controlled and sustained manner. They are biocompatible, biodegradable, and are …

Advances in diagnostics and drug discovery against resistant and latent tuberculosis infection

C Shleider Carnero Canales, J Marquez Cazorla… - Pharmaceutics, 2023 - mdpi.com
Latent tuberculosis infection (LTBI) represents a subclinical, asymptomatic mycobacterial
state affecting approximately 25% of the global population. The substantial prevalence of …