Antioxidant enzymes and cancer

M Asaduzzaman Khan, M Tania, D Zhang… - Chinese Journal of …, 2010 - Springer
Although oxidation is the most common biological and energy producing reaction, oxidative
stress is harmful to cell, because the products of oxidation such as free radicals and …

Enzyme targeting strategies for prevention and treatment of cancer: Implications for cancer therapy

MH Baig, M Adil, R Khan, S Dhadi, K Ahmad… - Seminars in cancer …, 2019 - Elsevier
Extensive growth of cancer in humans is a major cause of death. Numerous studies are
being conducted to improve the early diagnosis, prevention, and treatment of cancer. Recent …

Glutathione level and glutathione-dependent enzyme activities in blood serum of patients with gastrointestinal tract tumors

D Ścibior, M Skrzycki, M Podsiad, H Czeczot - Clinical Biochemistry, 2008 - Elsevier
OBJECTIVES: Glutathione (GSH) and enzymes cooperating with it–glutathione peroxidase
(GSHPx), glutathione S-transferase (GST) and glutathione reductase (GSHR)–play crucial …

Oxidant/antioxidant status of breast cancer patients in pre-and post-operative periods

J Didžiapetrienė, B Kazbarienė, R Tikuišis, A Dulskas… - Medicina, 2020 - mdpi.com
Background and Objectives: The purpose of this study is to evaluate the level of oxidative
stress before and after breast cancer surgery. Materials and Methods: Malondialdehyde …

Glutathione S-transferase alpha 4 induction by activator protein 1 in colorectal cancer

Y Yang, MM Huycke, TS Herman, X Wang - Oncogene, 2016 - nature.com
Glutathione S-transferase alpha 4 (GSTA4) is a phase II detoxifying enzyme that
metabolizes electrophiles and carcinogens including 4-hydroxy-2-nonenal (4-HNE), an …

Involvement of genetic factors and lifestyle on the occurrence of colorectal and gastric cancer

O Baroudi, A Benammar-Elgaaied - Critical reviews in oncology …, 2016 - Elsevier
Gastrointestinal cancers are diseases due to genetic and environmental factors. In this
present work we are interested in the influence of environmental factors on the occurrence of …

Differences between antioxidant defense parameters and specific trace element concentrations in healthy, benign, and malignant brain tissues

S Borković-Mitić, A Stojsavljević, L Vujotić, S Matić… - Scientific Reports, 2021 - nature.com
There are only a few reports examining the impact of oxidative stress in patients with benign
and malignant brain tumors. In this study we investigated whether there are changes in …

Genetic and molecular origins of colorectal Cancer among the Iranians: an update

MR Abbaszadegan, M Moghbeli - Diagnostic pathology, 2018 - Springer
Background Colorectal cancer (CRC) is one the leading causes of cancer related deaths
among Iranians. Despite the various progresses in new therapeutic methods, it has still a …

Oxidative alterations induced in vitro by the photodynamic reaction in doxorubicin-sensitive (LoVo) and -resistant (LoVoDX) colon adenocarcinoma cells

J Kulbacka, A Chwiłkowska, J Bar… - Experimental …, 2010 - journals.sagepub.com
In photodynamic therapy (PDT) a tumor-selective photosensitizer is administered and then
activated by exposure to a light source of appropriate wavelength. Multidrug resistance …

GSTM1 and GSTT1 polymorphisms as modifiers of age at diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC) in a homogeneous cohort of individuals …

R Felix, W Bodmer, NS Fearnhead… - Mutation Research …, 2006 - Elsevier
The variability in phenotype that occurs for so-called 'single-gene disorders' may be
because of germline alterations in numerous primary and “modifier” genes. Within HNPCC …