Molecularly Engineered Room-Temperature Phosphorescence for Biomedical Application: From the Visible toward Second Near-Infrared Window

B Chang, J Chen, J Bao, T Sun, Z Cheng - Chemical Reviews, 2023 - ACS Publications
Phosphorescence, characterized by luminescent lifetimes significantly longer than that of
biological autofluorescence under ambient environment, is of great value for biomedical …

Detection of hypoxia in cancer models: significance, challenges, and advances

I Godet, S Doctorman, F Wu, DM Gilkes - Cells, 2022 - mdpi.com
The rapid proliferation of cancer cells combined with deficient vessels cause regions of
nutrient and O2 deprivation in solid tumors. Some cancer cells can adapt to these extreme …

Quantification of oxygen depletion during FLASH irradiation in vitro and in vivo

X Cao, R Zhang, TV Esipova, SR Allu, R Ashraf… - International Journal of …, 2021 - Elsevier
Purpose Delivery of radiation at ultrahigh dose rates (UHDRs), known as FLASH, has
recently been shown to preferentially spare normal tissues from radiation damage compared …

Tumor hypoxia as a barrier in cancer therapy: why levels matter

T Hompland, CS Fjeldbo, H Lyng - Cancers, 2021 - mdpi.com
Simple Summary Hypoxia is a common feature of solid tumors and associated with poor
outcome in most cancer types and treatment modalities, including radiotherapy …

Dosimetry for FLASH radiotherapy: a review of tools and the role of radioluminescence and Cherenkov emission

MR Ashraf, M Rahman, R Zhang, BB Williams… - Frontiers in …, 2020 - frontiersin.org
While spatial dose conformity delivered to a target volume has been pushed to its practical
limits with advanced treatment planning and delivery, investigations in novel temporal dose …

The development of phosphorescent probes for in vitro and in vivo bioimaging

X Zhen, R Qu, W Chen, W Wu, X Jiang - Biomaterials science, 2021 - pubs.rsc.org
Phosphorescence is a process that slowly releases the photoexcitation energy after the
removal of the excitation source. Although transition metal complexes and purely organic …

Abnormal thermally-stimulated dynamic organic phosphorescence

H Wang, H Ma, N Gan, K Qin, Z Song, A Lv… - Nature …, 2024 - nature.com
Dynamic luminescence behavior by external stimuli, such as light, thermal field, electricity,
mechanical force, etc., endows the materials with great promise in optoelectronic …

Phosphorescent NIR emitters for biomedicine: Applications, advances and challenges

PS Chelushkin, JR Shakirova, IS Kritchenkov… - Dalton …, 2022 - pubs.rsc.org
Application of NIR (near-infrared) emitting transition metal complexes in biomedicine is a
rapidly developing area of research. Emission of this class of compounds in the “optical …

Photoreaction boosting phosphorescence cascade energy transfer based on cucurbit [8] uril biaxial polypseudorotaxane

WW Xing, HJ Wang, Z Liu, ZH Yu… - Advanced Optical …, 2023 - Wiley Online Library
Cascade energy capturers based on supramolecular assembly have recently generated
great research interest in the field of luminescent materials. Herein is reported a cucurbit [8] …

Afterglow/fluorescence dual-emissive ratiometric oxygen probe for tumor hypoxia imaging

Y Wen, S Zhang, W Yuan, W Feng, F Li - Analytical Chemistry, 2023 - ACS Publications
Hypoxia is a common feature of many diseases such as solid tumors. The measurement and
imaging of oxygen (O2) are extremely important for disease diagnosis and therapy …