Advanced multifunctional nano-lipid carrier loaded gel for targeted delivery of 5-flurouracil and cannabidiol against non-melanoma skin cancer

N Hasan, M Imran, A Sheikh, N Tiwari, A Jaimini… - Environmental …, 2023 - Elsevier
Non-melanoma skin cancer is one of the most common malignancies reported around the
globe. Current treatment therapies fail to meet the desired therapeutic efficacy due to high …

[HTML][HTML] Microemulsions for enhancing drug delivery of hydrophilic drugs: Exploring various routes of administration

KS Yadav, G Soni, D Choudhary, A Khanduri… - Medicine in Drug …, 2023 - Elsevier
Microemulsions are a promising drug delivery system that can be used to enhance the
bioavailability, solubility, and therapeutic efficacy of hydrophilic drugs. The downside of …

Enhanced transdermal delivery of lutein via nanoethosomal gel: Formulation optimization, in-vitro evaluation, and in-vivo assessment

A Nikhat, N Hasan, Z Iqbal, P Kesharwani… - Journal of Drug Delivery …, 2022 - Elsevier
Lutein has low oral bioavailability and penetration through the skin. Therefore, the major
objective is the development of ethosomal gel loaded with lutein to enhance dermal …

Improvement of Ferulic Acid Antioxidant Activity by Multiple Emulsions: In Vitro and In Vivo Evaluation

A Mancuso, MC Cristiano, R Pandolfo, M Greco… - Nanomaterials, 2021 - mdpi.com
Ferulic acid is a derivative of cinnamic acid showing efficacious anti-oxidant activity. It
catalyzes the stable phenoxy radical formation, upon absorption of ultraviolet light, giving the …

Nanostructured lipid carrier to overcome stratum corneum barrier for the delivery of agomelatine in rat brain; formula optimization, characterization and brain …

S Ahmed, S Mahmood, MD Ansari, A Gull… - International Journal of …, 2021 - Elsevier
The current work attempted to achieve bypassed hepatic metabolism, controlled release,
and boosted brain distribution of agomelatine by loading in NLC and administering via …

Nanocarrier based delivery of berberine: a critical review on pharmaceutical and preclinical characteristics of the bioactive

M Jawed Khan, A Hafeez… - Current Pharmaceutical …, 2023 - benthamdirect.com
Berberine (BBR) is an isoquinoline alkaloid with several therapeutic properties, including
anti-microbial, anti-diarrhea, anti-viral, anti-inflammatory, antihypertensive, anti-tumor, and …

Piper aduncum Essential Oil Rich in Dillapiole: Development of Hydrogel-Thickened Nanoemulsion and Nanostructured Lipid Carrier Intended for Skin Delivery

SB Carneiro, T Kreutz, RP Limberger, HF Teixeira… - Pharmaceutics, 2022 - mdpi.com
The essential oil extracted from the leaves of Piper aduncum, an aromatic plant from the
Amazon region, is rich in dillapiole and presents anti-inflammatory activity. In this study …

Development of Gelled-Oil Nanoparticles for the Encapsulation and Release of Berberine

DA Makeiff, B Smith, K Azyat, M Xia, SB Alam - ACS omega, 2023 - ACS Publications
In this study, a new drug carrier based on gelled-oil nanoparticles (GNPs) was designed and
synthesized for the encapsulation and release of the model hydrophobic drug, berberine …

Delivery Systems of Plant-Derived Antimicrobials

E Elmowafy, EM El-Marakby, HA Gad… - … Antimicrobials from Natural …, 2022 - Springer
The use of essential oils as antimicrobial agents is widely applied in medical field,
pharmaceutical industry, and food preservation. However, essential oils are hydrophobic …

A DoE-based development and characterization of Nadifloxacin-loaded transethosomal gel for the treatment of Acne vulgaris

S Patil, PM Dandagi, T Kazi, S Hulyalkar… - Future Journal of …, 2024 - Springer
Background The objective of this current research was to enhance the topical delivery of
Nadifloxacin (NDFX) by incorporating it into a transethosomal gel formulation. NDFX has …