Advances in mass spectrometry for lipidomics

SJ Blanksby, TW Mitchell - Annual Review of Analytical …, 2010 - annualreviews.org
Recent expansion in research in the field of lipidomics has been driven by the development
of new mass spectrometric tools and protocols for the identification and quantification of …

Desorption electrospray ionization and other ambient ionization methods: current progress and preview

DR Ifa, C Wu, Z Ouyang, RG Cooks - Analyst, 2010 - pubs.rsc.org
Mass spectrometry allows rapid chemical analysis of untreated samples in the ambient
environment. This is a result of recent rapid progress in ambient ionization techniques. The …

Use of mass spectrometry for imaging metabolites in plants

YJ Lee, DC Perdian, Z Song, ES Yeung… - The Plant …, 2012 - Wiley Online Library
We discuss and illustrate recent advances that have been made to image the distribution of
metabolites among cells and tissues of plants using different mass spectrometry …

Lipid imaging by mass spectrometry–a review

D Gode, DA Volmer - Analyst, 2013 - pubs.rsc.org
Mass spectrometry imaging (MSI) has proven to be extremely useful for applications such as
the spatial analysis of peptides and proteins in biological tissue, the performance …

Single-cell metabolic profiling of macrophages using 3D OrbiSIMS: correlations with phenotype

W Suvannapruk, MK Edney, DH Kim, DJ Scurr… - Analytical …, 2022 - ACS Publications
Macrophages are important immune cells that respond to environmental cues acquiring a
range of activation statuses represented by pro-inflammatory (M1) and anti-inflammatory …

Analytical techniques for single-cell metabolomics: state of the art and trends

A Amantonico, PL Urban, R Zenobi - Analytical and bioanalytical chemistry, 2010 - Springer
Single-cell metabolomics is an emerging field that addresses fundamental biological
questions and allows one to observe metabolic phenomena in heterogeneous populations …

Imaging lipids with secondary ion mass spectrometry

ML Kraft, HA Klitzing - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2014 - Elsevier
This review discusses the application of time-of-flight secondary ion mass spectrometry (TOF-
SIMS) and magnetic sector SIMS with high lateral resolution performed on a Cameca …

Unravelling prostate cancer heterogeneity using spatial approaches to lipidomics and transcriptomics

SM Mutuku, X Spotbeen, PJ Trim, MF Snel, LM Butler… - Cancers, 2022 - mdpi.com
Simple Summary Prostate cancer is a heterogenous disease in terms of disease
aggressiveness and therapy response, leading to dilemmas in treatment decisions. This …

SIMS imaging of the nanoworld: applications in science and technology

M Senoner, WES Unger - Journal of analytical atomic spectrometry, 2012 - pubs.rsc.org
Secondary Ion Mass Spectrometry (SIMS) enables surface chemical analysis of nano-scaled
objects and chemical imaging of nano-scaled details of natural or artificial objects. This …

Single-cell metabolomics analysis by microfluidics and mass spectrometry: recent new advances

D Feng, T Xu, H Li, X Shi, G Xu - Journal of Analysis and Testing, 2020 - Springer
Metabolomics at the single-cell level can analyze cellular metabolites, study the phenotypic
variations in individual cells and reveal phenomena and mechanisms that cannot be …