Post-COVID-19 depressive symptoms: epidemiology, pathophysiology, and pharmacological treatment

MG Mazza, M Palladini, S Poletti, F Benedetti - CNS drugs, 2022 - Springer
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic is still spreading worldwide
over 2 years since its outbreak. The psychopathological implications in COVID-19 survivors …

[HTML][HTML] Efficacy and safety of selective serotonin reuptake inhibitors in COVID-19 management: a systematic review and meta-analysis

J Deng, D Rayner, HB Ramaraju, U Abbas… - Clinical Microbiology …, 2023 - Elsevier
Background The efficacy of selective serotonin reuptake inhibitors (SSRIs) in the treatment
of acute COVID-19 is still under investigation, with conflicting results reported from …

Impact of COVID-19 on the liver and on the care of patients with chronic liver disease, hepatobiliary cancer, and liver transplantation: An updated EASL position paper

T Marjot, CS Eberhardt, T Boettler, LS Belli… - Journal of …, 2022 - Elsevier
The COVID-19 pandemic has presented a serious challenge to the hepatology community,
particularly healthcare professionals and patients. While the rapid development of safe and …

Sertraline modulates hippocampal plasticity via sigma 1 receptors, cellular stress and neurosteroids

Y Izumi, AM Reiersen, EJ Lenze, SJ Mennerick… - Translational …, 2024 - nature.com
In addition to modulating serotonin transport, selective serotonin reuptake inhibitors (SSRIs)
have multiple other mechanisms that may contribute to clinical effects, and some of these …

Overview of the potential use of fluvoxamine for COVID-19 and long COVID

K Hashimoto - Discover Mental Health, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) has presented a serious worldwide threat to
public health since its emergence in late 2019. From a safety point of view, drug repurposing …

Association of severe mental illness and septic shock case fatality rate in patients admitted to the intensive care unit: A national population-based cohort study

I Lakbar, M Leone, V Pauly, V Orleans… - PLoS …, 2023 - journals.plos.org
Background Patients with severe mental illness (SMI)(ie, schizophrenia, bipolar disorder, or
major depressive disorder) have been reported to have excess mortality rates from infection …

Medications modulating the acid sphingomyelinase/ceramide system and 28-day mortality among patients with SARS-CoV-2: an observational study

N Hoertel, K Rezaei, M Sánchez-Rico… - Pharmaceuticals, 2023 - mdpi.com
Prior evidence indicates the potential central role of the acid sphingomyelinase
(ASM)/ceramide system in the infection of cells with SARS-CoV-2. We conducted a …

Saving millions of lives but some resources squandered: emerging lessons from health research system pandemic achievements and challenges

SR Hanney, SE Straus, BJ Holmes - Health Research Policy and Systems, 2022 - Springer
During the SARS-CoV-2 pandemic, astonishingly rapid research averted millions of deaths
worldwide through new vaccines and repurposed and new drugs. Evidence use informed …

SSRIs differentially modulate the effects of pro-inflammatory stimulation on hippocampal plasticity and memory via sigma 1 receptors and neurosteroids

Y Izumi, AM Reiersen, EJ Lenze, SJ Mennerick… - Translational …, 2023 - nature.com
Certain selective serotonin reuptake inhibitors (SSRIs) have anti-inflammatory effects in
preclinical models, and recent clinical studies suggest that fluvoxamine can prevent …

COVID-19 therapeutics

D Focosi, M Franchini, F Maggi… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Since the emergence of COVID-19 in 2020, an unprecedented range of therapeutic options
has been studied and deployed. Healthcare providers have multiple treatment approaches …