There are now more Americans older than 65 years than at any other point in US history,
and the aging population is expected to increase rapidly over the next decade. 1 Aging …

This review focuses on the state‐of‐the‐art of the three major classes of gas contrast agents
used in magnetic resonance imaging (MRI)—hyperpolarized (HP) gas, molecular oxygen …

Background Patients often report persistent symptoms beyond the acute infectious phase of
COVID-19. Hyperpolarised 129Xe MRI provides a way to directly measure airway functional …

Rationale and Objectives Ventilation heterogeneity is impossible to detect with spirometry.
Alternatively, pulmonary ventilation can be imaged three-dimensionally using inhaled 129 …

Rationale: Inflammation and smooth muscle dysfunction are integral components of severe
asthma that contribute to luminal obstruction causing airflow limitation, ventilation …

In the last two decades, functional imaging of the lungs using hyperpolarized noble gases
has entered the clinical stage. Both helium (3 He) and xenon (129 Xe) gas have been …

In the past decade, hyperpolarized (HP) contrast agents have been under active
development for MRI applications to address the twin challenges of functional and …

Purpose To directly compare magnetic resonance (MR) imaging and computed tomography
(CT) parametric response map (PRM) measurements of gas trapping and emphysema in ex …

Developed over six decades ago, pulmonary oscillometry has re‐emerged as a noninvasive
and effort‐independent method for evaluating respiratory‐system impedance in patients with …

In this study, the effect of lung volume on quantitative measures of lung ventilation was
investigated using MRI with hyperpolarized 3He and 129Xe. Six volunteers were imaged …