Traumatic brain injury: progress and challenges in prevention, clinical care, and research
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …
neurological disorders, and poses a substantial public health burden. TBI is increasingly …
Blood biomarkers for mild traumatic brain injury: a selective review of unresolved issues
Background The use of blood biomarkers after mild traumatic brain injury (mTBI) has been
widely studied. We have identified eight unresolved issues related to the use of five …
widely studied. We have identified eight unresolved issues related to the use of five …
Blood biomarkers on admission in acute traumatic brain injury: relations to severity, CT findings and care path in the CENTER-TBI study
Background Serum biomarkers may inform and improve care in traumatic brain injury (TBI).
We aimed to correlate serum biomarkers with clinical severity, care path and imaging …
We aimed to correlate serum biomarkers with clinical severity, care path and imaging …
Neurofilament light as a biomarker in traumatic brain injury
P Shahim, A Politis, A Van Der Merwe, B Moore… - Neurology, 2020 - AAN Enterprises
Objective To determine whether serum neurofilament light (NfL) correlates with CSF NfL,
traumatic brain injury (TBI) diagnosis, injury severity, brain volume, and diffusion tensor …
traumatic brain injury (TBI) diagnosis, injury severity, brain volume, and diffusion tensor …
Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research
Executive summary A concerted effort to tackle the global health problem posed by traumatic
brain injury (TBI) is long overdue. TBI is a public health challenge of vast, but insufficiently …
brain injury (TBI) is long overdue. TBI is a public health challenge of vast, but insufficiently …
Serial sampling of serum protein biomarkers for monitoring human traumatic brain injury dynamics: a systematic review
Background The proteins S100B, neuron-specific enolase (NSE), glial fibrillary acidic
protein (GFAP), ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), and neurofilament light …
protein (GFAP), ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), and neurofilament light …
A serum protein biomarker panel improves outcome prediction in human traumatic brain injury
E Thelin, F Al Nimer, A Frostell, H Zetterberg… - Journal of …, 2019 - liebertpub.com
Brain-enriched protein biomarkers of tissue fate are being introduced clinically to aid in
traumatic brain injury (TBI) management. The aim of this study was to determine how …
traumatic brain injury (TBI) management. The aim of this study was to determine how …
S100B, GFAP, UCH-L1 and NSE as predictors of abnormalities on CT imaging following mild traumatic brain injury: a systematic review and meta-analysis of …
Biomarkers such as calcium channel binding protein S100 subunit beta (S100B), glial
fibrillary acidic protein (GFAP), ubiquitin c-terminal hydrolase L1 (UCH-L1) and neuron …
fibrillary acidic protein (GFAP), ubiquitin c-terminal hydrolase L1 (UCH-L1) and neuron …
GFAP and S100B: what you always wanted to know and never dared to ask
Traumatic brain injury (TBI) is a major global health issue, with outcomes spanning from
intracranial bleeding, debilitating sequelae, and invalidity with consequences for individuals …
intracranial bleeding, debilitating sequelae, and invalidity with consequences for individuals …
[HTML][HTML] Blood biomarkers for traumatic brain injury: A narrative review of current evidence
Introduction A blood-based biomarker (BBBM) test could help to better stratify patients with
traumatic brain injury (TBI), reduce unnecessary imaging, to detect and treat secondary …
traumatic brain injury (TBI), reduce unnecessary imaging, to detect and treat secondary …