Glioma is one of the most intractable types of cancer, due to delayed diagnosis at advanced
stages. The clinical symptoms of glioma are unclear and due to a variety of glioma subtypes …

Simple Summary The genomic landscape of the stem cell compartment and peritumoral
brain zone of glioblastoma is still incomplete. The key role of the stem component in tumor …

A framework for design of personalized cancer therapy requires the ability to predict the
sensitivity of a tumor to anticancer drugs. The predictive modeling of tumor sensitivity to anti …

OBJECTIVES: MicroRNAs (miRNAs) are negative regulators of protein coding genes which
are frequently deregulated in mammary cancers. Over-expression of microRNA-30b (hsa …

A collection of intracranial astrocytomas of different malignancy grades was analyzed for
copy number aberrations (CNA) in order to identify regions that are driving cancer …

Pharmacogenomics, the science of how genetic makeup influences an individual's reaction
to drugs, is an innovative tool for providing critical insights into how a patient will respond to …

A framework for design of personalized cancer therapy requires the ability to predict the
sensitivity of a tumor to anti-cancer drugs. The predictive modeling of tumor sensitivity to anti …

The regulatory interactions in a cell form a complicated system, and an important goal of
systems biology is to model and infer these interactions. The modeling and inference of …

With continued development and availability of genetic test offerings, there will be greater
need for physicians to help their patients interpret their results and to know when it is …