Epitope-based vaccine design: a comprehensive overview of bioinformatics approaches
Highlights•Epitope vaccines provide maximal therapeutic efficacy with minimal side
effects.•Reverse vaccinology can be used for designing epitope vaccines.•Computational …
effects.•Reverse vaccinology can be used for designing epitope vaccines.•Computational …
Immunoinformatics and vaccine development: an overview
AN Oli, WO Obialor, MO Ifeanyichukwu… - ImmunoTargets and …, 2020 - Taylor & Francis
The use of vaccines have resulted in a remarkable improvement in global health. It has
saved several lives, reduced treatment costs and raised the quality of animal and human …
saved several lives, reduced treatment costs and raised the quality of animal and human …
Vaxign2: the second generation of the first Web-based vaccine design program using reverse vaccinology and machine learning
E Ong, MF Cooke, A Huffman, Z Xiang… - Nucleic acids …, 2021 - academic.oup.com
Vaccination is one of the most significant inventions in medicine. Reverse vaccinology (RV)
is a state-of-the-art technique to predict vaccine candidates from pathogen's genome (s). To …
is a state-of-the-art technique to predict vaccine candidates from pathogen's genome (s). To …
A review of reverse vaccinology approaches for the development of vaccines against ticks and tick borne diseases
AE Lew-Tabor, MR Valle - Ticks and tick-borne diseases, 2016 - Elsevier
The field of reverse vaccinology developed as an outcome of the genome sequence
revolution. Following the introduction of live vaccinations in the western world by Edward …
revolution. Following the introduction of live vaccinations in the western world by Edward …
Vaxign-ML: supervised machine learning reverse vaccinology model for improved prediction of bacterial protective antigens
E Ong, H Wang, MU Wong, M Seetharaman… - …, 2020 - academic.oup.com
Motivation Reverse vaccinology (RV) is a milestone in rational vaccine design, and machine
learning (ML) has been applied to enhance the accuracy of RV prediction. However, ML …
learning (ML) has been applied to enhance the accuracy of RV prediction. However, ML …
Comparison of open-source reverse vaccinology programs for bacterial vaccine antigen discovery
Reverse Vaccinology (RV) is a widely used approach to identify potential vaccine
candidates (PVCs) by screening the proteome of a pathogen through computational …
candidates (PVCs) by screening the proteome of a pathogen through computational …
The impact of bioinformatics on vaccine design and development
RR María, CJ Arturo, JA Alicia, MG Paulina… - Vaccines, 2017 - books.google.com
Vaccines are the pharmaceutical products that offer the best cost‐benefit ratio in the pre‐-
vention or treatment of diseases. In that a vaccine is a pharmaceutical product, vaccine …
vention or treatment of diseases. In that a vaccine is a pharmaceutical product, vaccine …
Computational Methods in Immunology and Vaccinology: Design and Development of Antibodies and Immunogens
The design of new biomolecules able to harness immune mechanisms for the treatment of
diseases is a prime challenge for computational and simulative approaches. For instance, in …
diseases is a prime challenge for computational and simulative approaches. For instance, in …
PanRV: Pangenome-reverse vaccinology approach for identifications of potential vaccine candidates in microbial pangenome
Background A revolutionary diversion from classical vaccinology to reverse vaccinology
approach has been observed in the last decade. The ever-increasing genomic and …
approach has been observed in the last decade. The ever-increasing genomic and …
The combination of artificial intelligence and systems biology for intelligent vaccine design
Introduction A new body of evidence depicts the applications of artificial intelligence and
systems biology in vaccine design and development. The combination of both approaches …
systems biology in vaccine design and development. The combination of both approaches …