Migraine is a disabling primary headache disorder that directly affects more than one billion
people worldwide. Despite its widespread prevalence, migraine remains under-diagnosed …

Migraine is a complex condition in which genetic predisposition interacts with other
biological and environmental factors determining its course. A hyperresponsive brain cortex …

Migraine and neuropathic pain (NP) are both painful, disabling, chronic conditions which
exhibit some symptom similarities and are thus considered to share a common etiology. The …

Objective Migraine is a prevalent and disabling neurological disease. Its genesis is poorly
understood, and there remains unmet clinical need. We aimed to identify mechanisms and …

Background Clinical trials have shown that erenumab is effective and well-tolerated for the
preventive treatment of chronic migraine. To extend the results from clinical trials, we …

Background and Objectives: Migraine headaches are chronic neurological diseases that
reduce the quality of life by causing severe headaches and autonomic nervous system …

Background Monoclonal antibodies against calcitonin gene-related peptide (CGRP) or its
receptor (anti-CGRP (-R) mAbs) and small-molecule CGRP receptor antagonists (gepants) …

Objectives To comprehensively summarize and meta-analyze the concurrence across voxel-
based morphometric (VBM) neuroimaging studies of migraine. Methods Neuroimaging …

TRPA1 and TRPM8 are transient receptor potential channels expressed in trigeminal
neurons that are related to pathophysiology in migraine models. Here we use a mouse …

Background Despite the pervasiveness of migraine, the underlying pathophysiological
mechanisms initiating migraine attacks are far from well understood and are matter of …