Important advances in understanding the pathogenesis of chronic lymphocytic leukaemia in
the past two decades have led to the development of new prognostic tools and novel …

Richter syndrome (RS) is the development of an aggressive lymphoma in patients with
chronic lymphocytic leukemia (CLL). Two pathologic variants of RS are recognized: namely …

Background Acalabrutinib is a selective, covalent Bruton tyrosine-kinase inhibitor with
activity in chronic lymphocytic leukaemia. We compare the efficacy of acalabrutinib with or …

Richter syndrome (RS) derives from the rare transformation of chronic lymphocytic leukemia
(CLL) into an aggressive lymphoma, most commonly of the diffuse large B cell lymphoma …

Richter syndrome (RS) represents the development of diffuse large B-cell lymphoma in the
context of chronic lymphocytic leukemia. The scarcity of biologic information about RS has …

Richter's transformation (RT) is an aggressive lymphoma that occurs upon progression from
chronic lymphocytic leukemia (CLL). Transformation has been associated with genetic …

Nearly all information about patients with chronic lymphocytic leukaemia (CLL) who develop
diffuse large B‐cell lymphoma [R ichter syndrome (RS)] is derived from retrospective case …

The natural history, prognostication and optimal treatment of Richter transformation
developed from chronic lymphocytic leukemia (CLL) are not well defined. We report the …

Richter syndrome (RS) is defined as the transformation of chronic lymphocytic leukemia
(CLL) into an aggressive lymphoma, most commonly diffuse large B-cell lymphoma …

Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. Here, we
highlight important genetic alterations that contribute to tumorigenesis, clinical progression …