Objective To develop standardized treatment regimens for chronic nonbacterial
osteomyelitis (CNO), also known as chronic recurrent multifocal osteomyelitis (CRMO), to …

Abstract Purpose of Review To describe in detail the clinical synopsis and pathophysiology
of chronic non-bacterial osteomyelitis and SAPHO syndrome. Recent Findings Chronic non …

Objectives Chronic non-bacterial osteomyelitis (CNO) or chronic recurrent multifocal
osteomyelitis (CRMO) is an autoinflammatory disorder characterized by sterile bone …

Chronic inflammation during many diseases is associated with bone loss. While interferons
(IFNs) are often inhibitory to osteoclast formation, the complex role that IFN and interferon …

Chronic nonbacterial osteomyelitis (CNO; aka, chronic recurrent multifocal osteomyelitis) is
an inflammatory disorder that presents with bone pain arising from sterile osteomyelitis. It is …

Chronic nonbacterial osteomyelitis (CNO) is an inflammatory bone disorder that most
frequently affects children and adolescents. Chronic recurrent multifocal osteomyelitis …

Magnetic resonance imaging (MRI) is a powerful imaging modality in the evaluation of
musculoskeletal (MSK) soft tissue, joint, and bone infections. It allows prompt diagnosis and …

Chronic nonbacterial osteomyelitis (CNO) can cause significant morbidity, including bone
pain and damage. In the absence of clinical trials, treatments include non-steroidal anti …

Background Chronic nonbacterial osteomyelitis (CNO) is a rare, and impactful auto-
inflammatory bone disease occurring in children and adults. Clinical care for CNO is …

Chronic recurrent multifocal osteomyelitis (CRMO) is an auto-inflammatory disorder affecting
the skeleton of children and adolescents. Whole-body MRI (WBMRI) is key in the diagnosis …