This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …

Lysosomes are membrane-bound organelles with roles in processes involved in degrading
and recycling cellular waste, cellular signalling and energy metabolism. Defects in genes …

Primary cilia are solitary, immotile sensory organelles present on most cells in the body that
participate broadly in human health, physiology and disease. Cilia generate a unique …

Ag/Ag@ AgCl/ZnO hybrid nanostructures are embedded in a hydrogel by a simple two-step
technique. The Ag/Ag@ AgCl nanostructures are assembled in the hydrogel via ultraviolet …

The intracellular calcium ions (Ca 2+) act as second messenger to regulate gene
transcription, cell proliferation, migration and death. Accumulating evidences have …

Mitochondrial membranes define distinct structural and functional compartments. Cristae of
the inner mitochondrial membrane (IMM) function as independent bioenergetic units that …

Mitochondria and lysosomes are critical for cellular homeostasis, and dysfunction of both
organelles has been implicated in numerous diseases. Recently, interorganelle contacts …

Lysosomal acidification dysfunction has been implicated as a key driving factor in the
pathogenesis of neurodegenerative diseases, including Alzheimer's disease and …

One of the most difficult challenges in the biomedical field is bacterial infection, which
causes tremendous harm to human health. In this work, an injectable hydrogel is …

Lysosomes are catabolic organelles that contribute to the degradation of intracellular
constituents through autophagy and of extracellular components through endocytosis …