Abstract The Peroxisome Proliferator Activated Receptor alpha (PPARα) is a transcription
factor that plays a major role in metabolic regulation. This review addresses the functional …

Ethnopharmacological relevance Plants are a natural treasure trove; their secondary
metabolites participate in several pharmacological processes, making them a crucial …

This study investigated the effects of oleanolic acid (OA) on hepatic lipid metabolism and gut–
liver axis homeostasis in an obesity-related non-alcoholic fatty liver disease (NAFLD) …

Ursolic acid (UA) is a natural triterpene compound found in various fruits and vegetables.
There is a growing interest in UA because of its beneficial effects, which include anti …

Oleanolic (OA), ursolic (UA), and betulinic (BA) acids are three triterpenic acids (TAs) with
potential effects for treatment of type 2 diabetes (T2DM). Mechanistic studies showed that …

The mealworm beetle, Tenebrio molitor, is currently considered as a pest when infesting
stored grains or grain products. However, mealworms are now being promoted as a …

Background Non-alcoholic fatty liver disease (NAFLD) is one of the most prevalent liver
diseases around the world, and is closely associated with obesity, diabetes, and insulin …

Background: Metabolic syndrome is a combination of dysregulated cardiometabolic risk
factors characterized by dyslipidemia, impaired glucose tolerance, insulin resistance …

Ursolic acid (UA) is a well-studied natural pentacyclic triterpenoid found in herbs, fruit and a
number of traditional Chinese medicinal plants. UA has a broad range of biological activities …

Scope A natural carotenoid abundant in seafood, astaxanthin (AX), has hypolipidemic
activity, but its underlying mechanisms of action and protein targets are unknown. We …