Towards development of a novel universal medical diagnostic method: Raman spectroscopy and machine learning

NM Ralbovsky, IK Lednev - Chemical Society Reviews, 2020 - pubs.rsc.org
Many problems exist within the myriad of currently employed screening and diagnostic
methods. Further, an incredibly wide variety of procedures are used to identify an even …

The evolving use of electronic health records (EHR) for research

E Kim, SM Rubinstein, KT Nead… - Seminars in radiation …, 2019 - Elsevier
Electronic health records (EHR) have been implemented successfully in a majority of United
States healthcare systems in some form. There has been a rise in secondary uses of EHR …

[HTML][HTML] Raman spectroscopy: guiding light for the extracellular matrix

MS Bergholt, A Serio, MB Albro - Frontiers in bioengineering and …, 2019 - frontiersin.org
The extracellular matrix (ECM) consists of a complex mesh of proteins, glycoproteins, and
glycosaminoglycans, and is essential for maintaining the integrity and function of biological …

Porous Au–Ag Nanoparticles from Galvanic Replacement Applied as Single‐Particle SERS Probe for Quantitative Monitoring

L Wang, S Patskovsky, B Gauthier‐Soumis, M Meunier - Small, 2022 - Wiley Online Library
Plasmonic nanostructures have raised the interest of biomedical applications of surface‐
enhanced Raman scattering (SERS). To improve the enhancement and produce sensitive …

Deep convolutional neural networks for tongue squamous cell carcinoma classification using Raman spectroscopy

M Yu, H Yan, J Xia, L Zhu, T Zhang, Z Zhu, X Lou… - Photodiagnosis and …, 2019 - Elsevier
With deep convolutional neural networks and fiber optic Raman spectroscopy, this study
presents a novel classification method that discriminates tongue squamous cell carcinoma …

Accurate diagnosis of lung tissues for 2D Raman spectrogram by deep learning based on short-time Fourier transform

Y Qi, L Yang, B Liu, L Liu, Y Liu, Q Zheng, D Liu… - Analytica Chimica …, 2021 - Elsevier
Multivariate statistical analysis methods have an important role in spectrochemical analyses
to rapidly identify and diagnose cancer and the subtype. However, utilizing these methods to …

Image-guided Raman spectroscopy navigation system to improve transperineal prostate cancer detection. Part 1: Raman spectroscopy fiber-optics system and in situ …

F Picot, R Shams, F Dallaire, G Sheehy… - Journal of …, 2022 - spiedigitallibrary.org
Significance: The diagnosis of prostate cancer (PCa) and focal treatment by brachytherapy
are limited by the lack of precise intraoperative information to target tumors during biopsy …

Development and first in‐human use of a Raman spectroscopy guidance system integrated with a brain biopsy needle

J Desroches, É Lemoine, M Pinto… - Journal of …, 2019 - Wiley Online Library
Navigation‐guided brain biopsies are the standard of care for diagnosis of several brain
pathologies. However, imprecise targeting and tissue heterogeneity often hinder obtaining …

Raman spectroscopy: a personalized decision-making tool on clinicians' hands for in situ cancer diagnosis and surgery guidance

MA Kouri, E Spyratou, M Karnachoriti, D Kalatzis… - Cancers, 2022 - mdpi.com
Simple Summary Cancer still constitutes one of the main global health challenges. Novel
approaches towards understanding the molecular composition of the disease can be …

In situ Raman spectroscopy and machine learning unveil biomolecular alterations in invasive breast cancer

S David, T Tran, F Dallaire, G Sheehy… - Journal of …, 2023 - spiedigitallibrary.org
Significance As many as 60% of patients with early stage breast cancer undergo breast-
conserving surgery. Of those, 20% to 35% need a second surgery because of incomplete …