Chiral self-assembly of peptides: Toward the design of supramolecular polymers with enhanced chemical and biological functions
Chirality is one of the most important structural features in biological systems. Peptides, as a
class of small biomolecules, can self-assemble into various chiral supramolecular polymers …
class of small biomolecules, can self-assemble into various chiral supramolecular polymers …
Recent applications of retro-inverso peptides
Natural and de novo designed peptides are gaining an ever-growing interest as drugs
against several diseases. Their use is however limited by the intrinsic low bioavailability and …
against several diseases. Their use is however limited by the intrinsic low bioavailability and …
Peptide-22 and cyclic RGD functionalized liposomes for glioma targeting drug delivery overcoming BBB and BBTB
C Chen, Z Duan, Y Yuan, R Li, L Pang… - … applied materials & …, 2017 - ACS Publications
Chemotherapy outcomes for the treatment of glioma remain unsatisfied due to the inefficient
drug transport across BBB/BBTB and poor drug accumulation in the tumor site. Nanocarriers …
drug transport across BBB/BBTB and poor drug accumulation in the tumor site. Nanocarriers …
The recent advance of cell-penetrating and tumor-targeting peptides as drug delivery systems based on tumor microenvironment
Q Zhang, N Liu, J Wang, Y Liu, K Wang… - Molecular …, 2023 - ACS Publications
Cancer has become the primary reason for industrial countries death. Although first-line
treatments have achieved remarkable results in inhibiting tumors, they could have serious …
treatments have achieved remarkable results in inhibiting tumors, they could have serious …
Chiral-engineered supraparticles: Emerging tools for drug delivery
Highlights•Molecular chirality recognized in pharmacokinetics and pharmacodynamics.•
Supramolecular polymers (SPs) are excellent systems in biological system assembly.•Chiral …
Supramolecular polymers (SPs) are excellent systems in biological system assembly.•Chiral …
Liposome-based glioma targeted drug delivery enabled by stable peptide ligands
The treatment of glioma is one of the most challenging tasks in clinic. As an intracranial
tumor, glioma exhibits many distinctive characteristics from other tumors. In particular …
tumor, glioma exhibits many distinctive characteristics from other tumors. In particular …
[HTML][HTML] Dual receptor recognizing cell penetrating peptide for selective targeting, efficient intratumoral diffusion and synthesized anti-glioma therapy
Cell penetrating peptides (CPPs) were widely used for drug delivery to tumor. However, the
nonselective in vivo penetration greatly limited the application of CPPs-mediated drug …
nonselective in vivo penetration greatly limited the application of CPPs-mediated drug …
Retro-Inverso Isomer of Angiopep-2: A Stable d-Peptide Ligand Inspires Brain-Targeted Drug Delivery
The blood–brain barrier (BBB) prevents most drugs from reaching the site of central nervous
system (CNS) diseases, intensively confining the therapeutic efficiency. Angiopep-2 (here …
system (CNS) diseases, intensively confining the therapeutic efficiency. Angiopep-2 (here …
Cell-penetrating peptides in oncologic pharmacotherapy: A review
Cancer is the second leading cause of death in the world and its treatment is extremely
challenging, mainly due to its complexity. Cell-Penetrating Peptides (CPPs) are peptides …
challenging, mainly due to its complexity. Cell-Penetrating Peptides (CPPs) are peptides …
Construction of lanthanide-doped upconversion nanoparticle-Uelx Europaeus Agglutinin-I bioconjugates with brightness red emission for ultrasensitive in vivo …
R Tian, S Zhao, G Liu, H Chen, L Ma, H You, C Liu… - Biomaterials, 2019 - Elsevier
Lanthanide-doped upconversion nanoparticles (UCNPs)-based active targeting optical
bioimaging has attracted tremendous scientific interest because of its noninvasive real-time …
bioimaging has attracted tremendous scientific interest because of its noninvasive real-time …