Lung-on-a-chip: the future of respiratory disease models and pharmacological studies

J Shrestha, S Razavi Bazaz… - Critical reviews in …, 2020 - Taylor & Francis
Abstract Recently, organ-on-a-chip models, which are microfluidic devices that mimic the
cellular architecture and physiological environment of an organ, have been developed and …

Recent advances in lung-on-a-chip models

I Francis, J Shrestha, KR Paudel, PM Hansbro… - Drug Discovery …, 2022 - Elsevier
Highlights•Transition from conventional 2D models to 3D and advanced lung-on-a-chip
models.•Recent advances in lung-on-a-chip platforms and their implementation.•Numerous …

Advances and Current Challenges in Intestinal in vitro Model Engineering: A Digest

J Costa, A Ahluwalia - Frontiers in bioengineering and biotechnology, 2019 - frontiersin.org
The physiological environment of the intestine is characterized by its variegated
composition, numerous functions and unique dynamic conditions, making it challenging to …

miR-33-5p, a novel mechano-sensitive microRNA promotes osteoblast differentiation by targeting Hmga2

H Wang, Z Sun, Y Wang, Z Hu, H Zhou, L Zhang… - Scientific reports, 2016 - nature.com
MicroRNAs (miRNAs) interfere with the translation of specific target mRNAs and are thought
to thereby regulate many cellular processes. However, the role of miRNAs in osteoblast …

[HTML][HTML] Aging brain mechanics: Progress and promise of magnetic resonance elastography

LV Hiscox, H Schwarb, MDJ McGarry, CL Johnson - Neuroimage, 2021 - Elsevier
Novel neuroimaging techniques that can sensitivity characterize healthy brain aging and
detect subtle neuropathologies have enormous potential to assist in the early detection of …

Role of collagen in airway mechanics

L Liu, B Stephens, M Bergman, A May, T Chiang - Bioengineering, 2021 - mdpi.com
Collagen is the most abundant airway extracellular matrix component and is the primary
determinant of mechanical airway properties. Abnormal airway collagen deposition is …

Elastic poly (ε-caprolactone)-polydimethylsiloxane copolymer fibers with shape memory effect for bone tissue engineering

D Kai, MP Prabhakaran, BQY Chan, SS Liow… - Biomedical …, 2016 - iopscience.iop.org
A porous shape memory scaffold with biomimetic architecture is highly promising for bone
tissue engineering applications. In this study, a series of new shape memory polyurethanes …

Gelatin methacrylate hydrogel for tissue engineering applications—a review on material modifications

S Bupphathong, C Quiroz, W Huang, PF Chung… - Pharmaceuticals, 2022 - mdpi.com
To recreate or substitute tissue in vivo is a complicated endeavor that requires biomaterials
that can mimic the natural tissue environment. Gelatin methacrylate (GelMA) is created …

Hybrid and composite scaffolds based on extracellular matrices for cartilage tissue engineering

M Setayeshmehr, E Esfandiari, M Rafieinia… - … Engineering Part B …, 2019 - liebertpub.com
Cartilage consists of chondrocytes and a special extracellular matrix (ECM) having unique
biochemical, biophysical, and biomechanical properties that play a critical role in the …

Dynamic self-reinforcement of gene expression determines acquisition of cellular mechanical memory

CC Price, J Mathur, JD Boerckel, A Pathak… - Biophysical journal, 2021 - cell.com
Mechanotransduction describes activation of gene expression by changes in the cell's
physical microenvironment. Recent experiments show that mechanotransduction can lead to …