[HTML][HTML] The Epidemiology and Pathogenesis and Treatment of Pseudomonas aeruginosa Infections: An Update

D Reynolds, M Kollef - Drugs, 2021 - Springer
Pseudomonas aeruginosa is a Gram-negative bacterial pathogen that is a common cause of
nosocomial infections, particularly pneumonia, infection in immunocompromised hosts, and …

The microbiome-shaping roles of bacteriocins

S Heilbronner, B Krismer, H Brötz-Oesterhelt… - Nature Reviews …, 2021 - nature.com
The microbiomes on human body surfaces affect health in multiple ways. They include not
only commensal or mutualistic bacteria but also potentially pathogenic bacteria, which can …

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

L Evans, A Rhodes, W Alhazzani, M Antonelli… - Critical care …, 2021 - journals.lww.com
Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …

[HTML][HTML] Dysbiosis of a microbiota–immune metasystem in critical illness is associated with nosocomial infections

J Schlechte, AZ Zucoloto, I Yu, CJ Doig, MJ Dunbar… - Nature Medicine, 2023 - nature.com
Critically ill patients in intensive care units experience profound alterations of their gut
microbiota that have been linked to a high risk of hospital-acquired (nosocomial) infections …

[HTML][HTML] Tackling antimicrobial resistance in the COVID-19 pandemic

H Getahun, I Smith, K Trivedi, S Paulin… - Bulletin of the World …, 2020 - ncbi.nlm.nih.gov
Tackling antimicrobial resistance in the COVID-19 pandemic - PMC Back to Top Skip to main
content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main …

[HTML][HTML] How to use biomarkers of infection or sepsis at the bedside: guide to clinicians

P Póvoa, L Coelho, F Dal-Pizzol, R Ferrer… - Intensive care …, 2023 - Springer
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to infection. In this context, biomarkers could be considered as indicators of either …

Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 …

M Klompas, R Branson, K Cawcutt, M Crist… - Infection Control & …, 2022 - cambridge.org
The purpose of this document is to highlight practical recommendations to assist acute care
hospitals to prioritize and implement strategies to prevent ventilator-associated pneumonia …

[HTML][HTML] Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study

A Tabah, N Buetti, Q Staiquly, S Ruckly, M Akova… - Intensive care …, 2023 - Springer
Purpose In the critically ill, hospital-acquired bloodstream infections (HA-BSI) are associated
with significant mortality. Granular data are required for optimizing management, and …

[HTML][HTML] Acute complications and mortality in hospitalized patients with coronavirus disease 2019: a systematic review and meta-analysis

N Potere, E Valeriani, M Candeloro, M Tana, E Porreca… - Critical care, 2020 - Springer
Background The incidence of acute complications and mortality associated with COVID-19
remains poorly characterized. The aims of this systematic review and meta-analysis were to …

The pathophysiology of sepsis and precision-medicine-based immunotherapy

EJ Giamarellos-Bourboulis, AC Aschenbrenner… - Nature …, 2024 - nature.com
Sepsis remains a major cause of morbidity and mortality in both low-and high-income
countries. Antibiotic therapy and supportive care have significantly improved survival …