In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Within the human host, Legionella pneumophila replicates within alveolar macrophages,
leading to pneumonia. However, L. pneumophila is an aquatic generalist pathogen that …

The social amoeba Dictyostelium discoideum has been a preferred model organism during
the last 50 years, particularly for the study of cell motility and chemotaxis, phagocytosis and …

Phagocytic cells capture and kill most invader microbes within the bactericidal phagosome,
but some pathogens subvert killing by damaging the compartment and escaping to the …

Glycosylation of eukaryotic virus particles is common and influences their uptake, trafficking,
and immune recognition. In contrast, glycosylation of bacteriophage particles has not been …

The amoeba-resistant bacterium Legionella pneumophila causes Legionnaires' disease
and employs a type IV secretion system (T4SS) to replicate in the unique, ER-associated …

The soil amoeba Dictyostelium discoideum acts as both a predator and potential host for
diverse bacteria. We tested fifteen Pseudomonas strains that were isolated from transiently …

Introduction Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, remains
a serious threat to human health worldwide and the quest for new anti-tubercular drugs is an …

Mycobacterium bovis is the causative agent of bovine tuberculosis and the predominant
cause of zoonotic tuberculosis in people. Bovine tuberculosis occurs in farmed cattle but …

The infection course of Mycobacterium tuberculosis is highly dynamic and comprises
sequential stages that require damaging and crossing of several membranes to enable the …