Accurate diagnosis of multiple sclerosis requires careful attention to its differential diagnosis—
many disorders can mimic the clinical manifestations and paraclinical findings of this …

In recent years, the use of magnetic resonance imaging (MRI) for the diagnostic work-up of
multiple sclerosis (MS) has evolved considerably. The 2017 McDonald criteria show high …

Importance Multiple sclerosis (MS) misdiagnosis remains an important issue in clinical
practice. Objective To quantify the performance of cortical lesions (CLs) and central vein …

Introduction In multiple sclerosis (MS), paramagnetic rim lesions (PRLs) on MRI identify a
subset of chronic active lesions (CALs), which have been linked through clinical and …

The advent of highly effective disease modifying therapy has transformed the landscape of
multiple sclerosis (MS) care over the last two decades. However, there remains a critical …

The current diagnostic criteria for multiple sclerosis (MS) lack specificity, and this may lead to
misdiagnosis, which remains an issue in present-day clinical practice. In addition …

Axonal loss in multiple sclerosis (MS) is a key component of disease progression and
permanent neurologic disability. MS is a heterogeneous demyelinating and …

Focal lesions in both white and gray matter are characteristic of multiple sclerosis (MS).
Histopathological studies have helped define the main underlying pathological processes …

Accurate interpretation of a patient's clinical presentation and radiologic studies,
accompanied by knowledgeable and thoughtful application of the 2017 revised McDonald …

Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the
central nervous system (CNS) and the leading progressive neurologic condition a Division …