Important advances have been made in the understanding and management of adult
gliomas and primary CNS lymphomas—the two most common primary brain tumours …

Although low-grade gliomas (LGG) have a less aggressive course than do high-grade
gliomas, the outcome of these tumours is ultimately fatal in most patients. Both the tumour …

Preoperative MRI is one of the most important clinical results for the diagnosis and treatment
of glioma patients. The objective of this study was to construct a stable and validatable …

Background Outcome of low-grade glioma (WHO grade II) is highly variable, reflecting
molecular heterogeneity of the disease. We compared two different, single-modality …

Object The spontaneous prognostic factors and optimal therapeutic strategy for WHO Grade
II gliomas (GIIGs) have yet to be unanimously defined. Specifically, the role of resection is …

Diffuse low-grade glioma grows, migrates along white matter tracts, and progresses to high-
grade glioma. Rather than a “wait and see” policy, an aggressive attitude is now …

Objectives: Recent studies have shown that IDH1 and IDH2 mutations occur frequently in
gliomas, including low-grade gliomas. However, their impact on the prognosis and …

Low-grade gliomas cause considerable morbidity and most will recur after initial therapy. At
recurrence, low-grade gliomas can undergo transformation to high-grade gliomas (grade III …

Objective The aim of this study was to develop a radiomics signature for prediction of
progression-free survival (PFS) in lower-grade gliomas and to investigate the genetic …

Histological subtyping and grading by malignancy are the cornerstones of the World Health
Organization (WHO) classification of tumors of the central nervous system. They shall …