Nutrigenomics is the application of high-throughput genomics tools in nutrition research.
Applied wisely, it will promote an increased understanding of how nutrition influences …

The metal-responsive transcription factor-1 (MTF-1, also termed MRE-binding transcription
factor-1 or metal regulatory transcription factor-1) is a pluripotent transcriptional regulator …

The widespread occurrence of cadmium in the environment continues to pose a threat to
human health despite attempts at limiting its technological uses. The biologically significant …

Encyclopedia of Dietary Supplements presents peer-reviewed, objective entries that
rigorously examine the most significant scientific research on basic chemical, preclinical …

Zinc/cysteine coordination environments in proteins are redox-active. Oxidation of the sulfur
ligands mobilizes zinc, while reduction of the oxidized ligands enhances zinc binding …

Iron, copper, and zinc are all essential nutrients. The electron transfer properties of iron and
copper are fundamental to processes such as respiration and photosynthesis. Zinc forms the …

Exposure assessment is often considered the weakest link in risk assessment. It is important
for investigators to continue to utilize the full potential of biomarkers for chemicals whose …

The regulation of divalent zinc has been observed in a wide range of organisms. Since this
metal is an essential nutrient, but also toxic in excess, zinc homeostasis is crucial for normal …

Metallothioneins are small, cysteine-rich proteins that avidly bind heavy metals such as zinc,
copper, and cadmium to reduce their concentration to a physiological or nontoxic level …

SLC39A8 is an evolutionarily highly conserved gene that encodes the ZIP8 metal cation
transporter in all vertebrates. SLC39A8 is ubiquitously expressed, including pluripotent …