AD Viny, RL Levine - The Cancer Journal, 2014 - journals.lww.com
In the last decade, genomic studies have identified multiple recurrent somatic mutations in myeloproliferative neoplasms (MPNs). Beginning with the discovery of the JAK2 V617F …
Primary myelofibrosis (PM) is a myeloproliferative neoplasm characterized by stem cell- derived clonal neoplasms. Several factors are involved in diagnosing PM, including physical …
Y Qin, X Wang, C Zhao, C Wang, Y Yang - International journal of …, 2015 - Springer
To assess the effect of JAK2V617F on different thrombotic risks in essential thrombocythemia (ET) patients, we identified eligible studies from several databases …
G Cetin, T Ozkan, S Turgut, M Ali Cikrikcioglu… - Molecular biology …, 2014 - Springer
Essential thrombocythemia (ET) is an entity of classic Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs), characterized by thrombocytosis with megakaryocytic …
High‐throughput DNA sequence analysis was used to screen for TET2 mutations in peripheral blood derived DNA from 97 patients with BCR‐ABL‐negative myeloproliferative …
KB Payzin, K Savasoglu, I Alacacioglu… - … Myeloma and Leukemia, 2014 - Elsevier
Abstract Introduction/Background The aim of this study was to investigate the presence of Janus kinase 2 (JAK2) V617F mutation in patients with break point cluster region-abelson …
A Quintás-Cardama - Leukemia Research, 2013 - Elsevier
The acquired recurrent mutation, JAK2 V617F, is the most frequent mutation associated with myeloproliferative neoplasms (MPNs). JAK2 signaling is critical in normal hematopoiesis …
JH Ohyashiki, M Yoneta, H Hisatomi, T Iwabuchi… - BMC Medical …, 2012 - Springer
Background Polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF) are myeloproliferative neoplasms (MPNs) characterized in most cases …