Leukocytosis and thrombosis in essential thrombocythemia and polycythemia vera: a systematic review and meta-analysis

A Carobbio, A Ferrari, A Masciulli, A Ghirardi… - Blood …, 2019 - ashpublications.org
In the last years, a growing amount of evidence has been produced regarding the role of
leukocytosis as a risk factor for thrombosis in patients with myeloproliferative neoplasms …

Genetics of myeloproliferative neoplasms

AD Viny, RL Levine - The Cancer Journal, 2014 - journals.lww.com
In the last decade, genomic studies have identified multiple recurrent somatic mutations in
myeloproliferative neoplasms (MPNs). Beginning with the discovery of the JAK2 V617F …

Application of Fourier Transform InfraRed spectroscopy of machine learning with Support Vector Machine and principal components analysis to detect biochemical …

Z Guleken, Z Ceylan, A Aday, AG Bayrak… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Primary myelofibrosis (PM) is a myeloproliferative neoplasm characterized by stem cell-
derived clonal neoplasms. Several factors are involved in diagnosing PM, including physical …

Molecular genetics of thrombotic myeloproliferative neoplasms: Implications in precision oncology

YC Chia, MJ Siti Asmaa, M Ramli, PY Woon, MF Johan… - Diagnostics, 2023 - mdpi.com
Classical BCR-ABL-negative myeloproliferative neoplasms (MPN) include polycythaemia
vera, essential thrombocythaemia, and primary myelofibrosis. Unlike monogenic disorders …

The impact of JAK2V617F mutation on different types of thrombosis risk in patients with essential thrombocythemia: a meta-analysis

Y Qin, X Wang, C Zhao, C Wang, Y Yang - International journal of …, 2015 - Springer
To assess the effect of JAK2V617F on different thrombotic risks in essential
thrombocythemia (ET) patients, we identified eligible studies from several databases …

Evaluation of clinical and laboratory findings with JAK2 V617F mutation as an independent variable in essential thrombocytosis

G Cetin, T Ozkan, S Turgut, M Ali Cikrikcioglu… - Molecular biology …, 2014 - Springer
Essential thrombocythemia (ET) is an entity of classic Philadelphia chromosome-negative
myeloproliferative neoplasms (MPNs), characterized by thrombocytosis with megakaryocytic …

TET2 Mutations in Ph‐Negative Myeloproliferative Neoplasms: Identification of Three Novel Mutations and Relationship with Clinical and Laboratory Findings

A Patriarca, D Colaizzo, G Tiscia… - BioMed Research …, 2013 - Wiley Online Library
High‐throughput DNA sequence analysis was used to screen for TET2 mutations in
peripheral blood derived DNA from 97 patients with BCR‐ABL‐negative myeloproliferative …

JAK2 V617F mutation status of 232 patients diagnosed with chronic myeloproliferative neoplasms

KB Payzin, K Savasoglu, I Alacacioglu… - … Myeloma and Leukemia, 2014 - Elsevier
Abstract Introduction/Background The aim of this study was to investigate the presence of
Janus kinase 2 (JAK2) V617F mutation in patients with break point cluster region-abelson …

The role of Janus kinase 2 (JAK2) in myeloproliferative neoplasms: therapeutic implications

A Quintás-Cardama - Leukemia Research, 2013 - Elsevier
The acquired recurrent mutation, JAK2 V617F, is the most frequent mutation associated with
myeloproliferative neoplasms (MPNs). JAK2 signaling is critical in normal hematopoiesis …

The C allele of JAK2 rs4495487 is an additional candidate locus that contributes to myeloproliferative neoplasm predisposition in the Japanese population

JH Ohyashiki, M Yoneta, H Hisatomi, T Iwabuchi… - BMC Medical …, 2012 - Springer
Background Polycythemia vera (PV), essential thrombocythemia (ET), and primary
myelofibrosis (PMF) are myeloproliferative neoplasms (MPNs) characterized in most cases …