Carbonyl transformations involving enolates and/or enamines have been used for various
types of bond‐forming reactions. In this account, catalysts and catalyst systems that have …

Enantioselective Mannich reactions of pyruvates catalyzed by amine-based catalyst
systems, in which pyruvates act as nucleophiles, are reported. The reactions of pyruvates …

The organocatalytic enantio-and diastereoselective cycloetherification of 1, 3-
cyclohexanedione-bearing enones involving the in situ generation of chiral cyanohydrins …

Acid-catalyzed intramolecular reactions of isoindolinone-derived hydroxylactam derivatives
bearing enones or enals that afford spiro isoindolinone derivatives and related molecules …

We describe herein the first asymmetric total synthesis and biological evaluation of the
natural PDE4 inhibitor toddacoumalone and its stereoisomers. The key step of the total …

We demonstrated that the loading amounts and concentrations of reactant 1, 3-
cyclohexanedione affect reaction rates and outcomes. In certain cases, reactions with higher …

Catalytic asymmetric α-regioselective Michael additions of vinylogous α-ketoester enolate
are described herein. With 0.1–1.0 mol% loadings of a chiral bifunctional organocatalyst, the …

We have developed and investigated a catalytic desymmetrization reaction strategy that
affords functionalized decalin derivatives with high enantioselectivities from C2-symmetric …

The decalin skeleton is found in numerous bioactive molecules. The present study describes
a multicomponent all-carbon cascade and sequential annulation involving …

Control of chemical reactions is necessary to obtain designer chemical transformation
products and for preventing decomposition and isomerization reactions of compounds of …