The crystalline lens is a transparent and refractive biconvex structure formed by lens
epithelial cells (LECs) and lens fibers. Lens opacity, also known as cataracts, is the leading …

In the human eye, a transparent cornea and lens combine to form the" refracton" to focus
images on the retina. This requires the refracton to have a high refractive index" n," mediated …

Mock cataract surgery provides a unique ex vivo model for studying wound repair in a
clinically relevant setting. Here wound healing involves a classical collective migration of the …

Microtubules are cytoskeletal elements known as drivers of directed cell migration, vesicle
and organelle trafficking, and mitosis. In this review, we discuss new research in the lens …

Following injury, mesenchymal repair cells are activated to function as leader cells that
modulate wound healing. These cells have the potential to differentiate to myofibroblasts …

The primary function of the lens resides in its transparency and ability to focus light on the
retina. These require both that the lens cells contain high concentrations of densely packed …

Vascular endothelial (VE)–cadherin forms homotypic adherens junctions (AJs) in the
endothelium, whereas N-cadherin forms heterotypic adhesion between endothelial cells …

The eye lens is a transparent and avascular organ in the front of the eye that is responsible
for focusing light onto the retina in order to transmit a clear image. A monolayer of epithelial …

Lens, an avascular tissue involved in light transmission, generates an internal
microcirculatory system to promote ion and fluid circulation, thus providing nutrients to …

Cadherins constitute a family of transmembrane proteins that mediate calcium-dependent
cell-cell adhesion. The extracellular domain of cadherins consists of extracellular cadherin …