[HTML][HTML] Peritumoral microenvironment in high-grade gliomas: From flairectomy to microglia–glioma cross-talk

R Altieri, D Barbagallo, F Certo, G Broggi, M Ragusa… - Brain sciences, 2021 - mdpi.com
Cellular composition and molecular signatures of the glioma core compared with infiltrative
margins are different, and it is well known that the tumor edge is enriched in microglia. In this …

[HTML][HTML] Patient-derived explants as a precision medicine patient-proximal testing platform informing cancer management

AR Templeton, PL Jeffery, PB Thomas… - Frontiers in …, 2021 - frontiersin.org
Precision medicine approaches that inform clinical management of individuals with cancer
are progressively advancing. Patient-derived explants (PDEs) provide a patient-proximal ex …

[HTML][HTML] Distinct gene expression patterns of ion channels and cytokines in rat primary sensory neurons during development of bone cancer and cancer pain

M Zhai, S Yang, S Lin, H Zhu, L Xu, H Liao… - Frontiers in Molecular …, 2021 - frontiersin.org
Cancer and cancer pain processes a major clinical challenge and the underlined
mechanisms of pathogenesis remain elusive. We examined the specific changes in the …

[HTML][HTML] Glioblastoma and the search for non-hypothesis driven combination therapeutics in academia

T Johanssen, L McVeigh, S Erridge, G Higgins… - Frontiers in …, 2023 - frontiersin.org
Glioblastoma (GBM) remains a cancer of high unmet clinical need. Current standard of care
for GBM, consisting of maximal surgical resection, followed by ionisation radiation (IR) plus …

[HTML][HTML] Glioblastoma tissue slice tandem-cultures for quantitative evaluation of inhibitory effects on invasion and growth

V Sidorcenco, L Krahnen, M Schulz, J Remy, D Kögel… - Cancers, 2020 - mdpi.com
Simple Summary Glioblastomas are very malignant and essentially incurable brain tumors.
One problem is the extensive penetration of tumor cells into the adjacent normal brain …

RNA sequencing of glioblastoma tissue slice cultures reveals the effects of treatment at the transcriptional level

S Haehnel, M Rade, N Kaiser, K Reiche… - FEBS Open …, 2022 - Wiley Online Library
One of the major challenges in cancer research is finding models that closely resemble
tumors within patients. Human tissue slice cultures are a promising approach to provide a …

Organotypische Schnittkulturen aus Glioblastomgewebe als präklinisches Testsystem

S Hähnel - 2023 - ul.qucosa.de
Abstract (DE) Glioblastoma multiforme (GBM) ist der häufigste bösartige Hirntumor bei
Erwachsenen. Unbehandelt liegt das mediane Überleben bei circa drei Monaten. Mithilfe …

[PDF][PDF] Выпускная квалификационная работа бакалавра

ИМ Спивак, СН Алексахина - core.ac.uk
Рак легкого занимает позицию одного из самых частых онкологических
новообразований: ежегодно диагностируется более 2 миллионов случаев [Globocan …

[PDF][PDF] Development of a model of organotypic tissue cultures to determine the chemosensitivity of non-small-cell lung tumors

BS Vladimirovna - 2021 - dspace.spbu.ru
Worldwide, lung cancer remains to be one of the most common cancers diagnosed. Despite
the success with targeted therapies, cytostatic drugs are still one of the main forms of …

[PDF][PDF] 多靶点全景数字病理: 从原理到应用

张新华, 李才伟, 张瑜, 黄胜男, 石晗, 吴俊楠… - 中国光学(中 …, 2022 - chineseoptics.net.cn
数字病理凭借其便捷的存储, 管理, 浏览, 传输等特点, 为远程病理会诊及联合会诊带来了新契机.
然而, 显微镜的视场有限, 在保证分辨率的前提下, 无法兼顾全景成像. 全景数字病理的提出弥补 …