The effect of stiffened diabetic red blood cells on wall shear stress in a reconstructed 3D microaneurysm

B Czaja, J de Bouter, M Heisler… - Computer Methods in …, 2022 - Taylor & Francis
Blood flow within the vasculature of the retina has been found to influence the progression of
diabetic retinopathy. In this research cell resolved blood flow simulations are used to study …

Red blood cell and platelet diffusivity and margination in the presence of cross-stream gradients in blood flows

G Závodszky, B van Rooij, B Czaja, V Azizi… - Physics of …, 2019 - pubs.aip.org
The radial distribution of cells in blood flow inside vessels is highly non-homogeneous. This
leads to numerous important properties of blood, yet the mechanisms shaping these …

Interplay of deformability and adhesion on localization of elastic micro-particles in blood flow

H Ye, Z Shen, Y Li - Journal of Fluid Mechanics, 2019 - cambridge.org
The margination and adhesion of micro-particles (MPs) have been extensively investigated
separately, due to their important applications in the biomedical field. However, the cascade …

Combined electromechanically driven pulsating flow of nonlinear viscoelastic fluids in narrow confinements

V Kumar, J Mukherjee, SK Sinha… - Journal of the Royal …, 2022 - royalsocietypublishing.org
Controlled microscale transport is at the core of many scientific and technological
advancements, including medical diagnostics, separation of biomolecules, etc., and often …

A continuum-based numerical simulation of blood plasma separation in a complex microdevice: Quantification of bifurcation law

SP Yadav, A Sharma, A Agrawal - International Communications in Heat …, 2024 - Elsevier
This study introduces a continuum-based two-fluid method to investigate blood flow within a
microchannel specifically engineered for blood plasma separation. The simulations …

Numerical simulation of cellular blood flow in curved micro-vessels with saccular aneurysms: Effect of curvature degree and hematocrit level

A Elhanafy, S Elsagheer, S Ookawara, S Nada - Biomicrofluidics, 2024 - pubs.aip.org
The dynamics of cellular blood flow in curved vessels considerably differ from those in
straight vessels. It is reported that clotting development is significantly affected by vessel …

The impact of arterial flow complexity on flow diverter outcomes in aneurysms

KJ Chodzyǹski, P Uzureau, V Nuyens, A Rousseau… - Scientific reports, 2020 - nature.com
The flow diverter is becoming a standard device for treating cerebral aneurysms. The aim of
this in vitro study was to evaluate the impact of flow complexity on the effectiveness of flow …

A Decision Tree Model to Help Treatment Decision-Making for Unruptured Intracranial Aneurysms: A Multi-center, Long-Term Follow-up Study in a Large Chinese …

Z Wen, X Nie, L Chen, P Liu, C Lan… - Translational Stroke …, 2024 - Springer
Chinese population have a high prevalence of unruptured intracranial aneurysm (UIA).
Clinical and imaging risk factors predicting UIA growth or rupture are poorly understood in …

Review on Blood Flow Dynamics in Lab-on-a-Chip Systems: An Engineering Perspective

BJ Lai, LT Zhu, Z Chen, B Ouyang… - Chem & Bio …, 2024 - ACS Publications
Under different transport mechanisms, blood flow dynamics, heavily linked to the flow shear
rate conditions, in “lab-on-a-chip”(LOC) systems are found to result in varying transport …

Simulating initial steps of platelet aggregate formation in a cellular blood flow environment

CJ Spieker, K Asteriou, G Zav́odszky - International Conference on …, 2023 - Springer
The mechano-chemical process of clot formation is relevant in both hemostasis and
thrombosis. The initial phase of thrombus formation in arterial thrombosis can be described …