Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine encoded within a
functionally polymorphic genetic locus. MIF was initially recognized as a cytokine generated …

Blood clotting is a finely regulated process that is essential for hemostasis. However, when
dysregulated or spontaneous, it promotes thrombotic disorders. The fact that these are …

Mammals evolved in the face of fluctuating food availability. How the immune system adapts
to transient nutritional stress remains poorly understood. Here, we show that memory T cells …

Red blood cells (RBCs) have been shown to affect immune function and can induce
inflammatory responses after transfusion. The transfusion of washed RBCs can significantly …

Platelet concentrates (PCs), mostly represented by platelet-rich plasma (PRP) and platelet-
rich fibrin (PRF) are autologous biological blood-derived products that may combine …

Recent advancements highlight the intricate interplay between the extracellular matrix
(ECM) and immune responses, notably in respiratory diseases such as asthma and Chronic …

Neutrophil extracellular traps (NETs) evolved as a unique effector mechanism contributing to
resistance against infection that can also promote tissue damage in inflammatory conditions …

Autologous biologics, defined as platelet-rich plasma (PRP) and bone marrow aspirate
concentrate (BMC), are cell-based therapy treatment options in regenerative medicine …

Eukaryotic cells are defined as cells containing distinct nuclei and other membranous
organelles. However, red blood cells (RBCs) lack a nucleus and organelles—perhaps to …

Macrophage migration inhibitory factor (MIF) is a pro-inflammatory factor produced by
residual red blood cell lysis, which can significantly influence the curative effect of Platelet …