The human organism comprises various physiological and organ systems, each with its own
structural organization and functional complexity, leading to complex, transient, fluctuating …

Platelet extracellular vesicles (PEVs) generated upon platelet activation may play a role in
inflammatory pathologies such as atherosclerosis. Oxidized low-density lipoprotein (oxLDL) …

Objectives: Diabetic patients are often diagnosed with several comorbidities. The aim of the
present study was to investigate the relationship between different combinations of risk …

This paper describes the implementation of a comprehensive clinical decision support
system (CDSS) for the risk factors prediction of comorbidities related to obesity and for the …

One of the principal goals of Precision Medicine is to stratify patients by accounting for
individual variability. However, extracting meaningful information from Real-World Data …

Delivering a clinically impactful cell number is a major design challenge for cell
macroencapsulation devices for Type 1 diabetes. It is important to understand the transplant …

Introduction India currently has more than 74.2 million people with Type 2 Diabetes Mellitus
(T2DM). This is predicted to increase to 124.9 million by 2045. In combination with …

Dementia is a highly prevalent condition with devastating clinical and socioeconomic
sequela. It is expected to triple in prevalence by 2050. No treatment is currently known to be …

Aims Chronic heart failure (CHF) has an increasing burden of comorbidities, which affect
clinical outcomes. Few studies have focused on the clustering and hierarchical management …

We present the Patient Trajectory Analysis Library (PTRA), a software package for
explorative analysis of patient development. PTRA provides the tools for extracting …