Mechanisms and consequences of sex differences in immune responses
Biological sex differences refer to differences between males and females caused by the sex
chromosome complement (that is, XY or XX), reproductive tissues (that is, the presence of …
chromosome complement (that is, XY or XX), reproductive tissues (that is, the presence of …
Sex differences in airway disease: estrogen and airway surface liquid dynamics
BJ Harvey, NG McElvaney - Biology of sex Differences, 2024 - Springer
Biological sex differences exist for many airway diseases in which females have either
worse or better health outcomes. Inflammatory airway diseases such as cystic fibrosis (CF) …
worse or better health outcomes. Inflammatory airway diseases such as cystic fibrosis (CF) …
Using big sequencing data to identify chronic SARS-Coronavirus-2 infections
The evolution of SARS-Coronavirus-2 (SARS-CoV-2) has been characterized by the
periodic emergence of highly divergent variants. One leading hypothesis suggests these …
periodic emergence of highly divergent variants. One leading hypothesis suggests these …
[HTML][HTML] The SARS-CoV-2 Spike protein induces long-term transcriptional perturbations of mitochondrial metabolic genes, causes cardiac fibrosis, and reduces …
Background As the pandemic evolves, post-acute sequelae of CoV-2 (PASC) including
cardiovascular manifestations have emerged as a new health threat. This study aims to …
cardiovascular manifestations have emerged as a new health threat. This study aims to …
Cytokine release syndrome after treatment with immune checkpoint inhibitors: An observational cohort study of 2672 patients from Karolinska University Hospital in …
O Hamida, F Karlsson, A Lundqvist, M Gerling… - …, 2024 - Taylor & Francis
Immune checkpoint inhibitors (ICIs) are linked to diverse immune-related adverse events
(irAEs). Rare irAEs surface first in clinical practice. Here, we systematically studied the rare …
(irAEs). Rare irAEs surface first in clinical practice. Here, we systematically studied the rare …
Elevated levels of cytotoxicity, cytokines, and anti-SARS-CoV-2 antibodies in mild cases of COVID-19
MA Fernández-Rojas, G Ávila… - Viral …, 2023 - liebertpub.com
Current evidence shows higher production of cytokines and antibodies against severe acute
respiratory coronavirus 2 (SARS-CoV-2) in severe and critical cases of Coronavirus Disease …
respiratory coronavirus 2 (SARS-CoV-2) in severe and critical cases of Coronavirus Disease …
Former SARS-CoV-2 Infection Was Related to Decreased VO2 Peak and Exercise Hypertension in Athletes
K Keller, O Friedrich, J Treiber, A Quermann… - Diagnostics, 2023 - mdpi.com
The impact of former COVID-19 infection on the performance of athletes is not fully
understood. We aimed to identify differences in athletes with and without former COVID-19 …
understood. We aimed to identify differences in athletes with and without former COVID-19 …
Fear of COVID-19 among professional caregivers of the elderly in Central Alentejo, Portugal
Abstract The coronavirus disease 2019 (COVID-19) has infected many institutionalised
elderly people. In Portugal, the level of pandemic fear among professional caregivers of the …
elderly people. In Portugal, the level of pandemic fear among professional caregivers of the …
[HTML][HTML] Cardiac damage and tropism of severe acute respiratory syndrome coronavirus 2
M Tangos, M Jarkas, I Akin, I El-Battrawy… - Current Opinion in …, 2024 - Elsevier
Highlights•Myocardial damage is a typical cardiac manifestation following SARS-CoV-2
infection.•Mechanisms include inflammation, oxidative stress, innate immune response …
infection.•Mechanisms include inflammation, oxidative stress, innate immune response …
A preclinical systematic review and meta-analysis assessing the effect of biological sex in lipopolysaccharide-induced acute lung injury
E Kuhar, N Chander, DJ Stewart… - … of Physiology-Lung …, 2024 - journals.physiology.org
It is unclear what effect biological sex has on outcomes of acute lung injury (ALI). Clinical
studies are confounded by their observational design. We addressed this knowledge gap …
studies are confounded by their observational design. We addressed this knowledge gap …