1α, 25-Dihydroxyvitamin D3 [1, 25-(OH) 2D3], the active metabolite of vitamin D3, is known
for the maintenance of mineral homeostasis and normal skeletal architecture. However …

The active form of vitamin D3, 1, 25-dihydroxyvitamin D3, is a major regulator of bone and
calcium homeostasis. In addition, this hormone also inhibits the proliferation and stimulates …

Background: Vitamin D exerts multiple beneficial effects in humans, including neuronal,
immune, and bone homeostasis and the regulation of cardiovascular functions. Recent …

BACKGROUND: Eldecalcitol is an analog of 1, 25-dihydroxyvitamin D3 that improves bone
mineral density; however, the effect of eldecalcitol on the risk of fractures is unclear. The …

Vitamin D plays a major role in the regulation of mineral homeostasis and affects bone
metabolism. Most effects of vitamin D have been attributed to the 1, 25-dihydroxyvitamin D3 …

Royal jelly (RJ) has been used worldwide for many years as medical products, health foods
and cosmetics. Since RJ contains testosterone and has steroid hormone‐type activities, we …

Active forms of vitamin D enhance osteoclastogenesis in vitro and in vivo through the vitamin
D receptor (VDR) in osteoblast-lineage cells consisting of osteoblasts and osteocytes. This …

Context: ED-71 has been shown to increase lumbar bone mineral density (BMD) in
osteoporotic subjects. However, vitamin D insufficiency might have influenced the effect of …

Although active vitamin D drugs have been used for the treatment of osteoporosis, how the
vitamin D receptor (VDR) regulates bone cell function remains largely unknown. Using …

Several compounds are produced along the complex pathways of vitamin D 3 metabolism,
and synthetic analogs have been generated to improve kinetics and/or vitamin D receptor …