Complications from malaria parasite infections still cost the lives of close to half a million
people every year. The most severe is cerebral malaria (CM). Employing murine models of …

Background Malaria is a serious parasitic infection affecting millions of people worldwide
each year. Cerebral malaria is the most severe complication of Plasmodium infections …

In acute Plasmodium falciparum (P. falciparum) malaria, the pro-and anti-inflammatory
immune pathways must be delicately balanced so that the parasitemia is controlled without …

Cerebral malaria (CM) is the most severe manifestation of infection with Plasmodium,
however its pathogenesis is still not completely understood. microRNA (miRNA) have been …

In the last decades, extracellular vesicles have emerged as important elements in cell–cell
communication and as key players in disease pathogenesis via transmission of their cargo …

Intravenous artesunate is effective against cerebral malaria (CM), but high mortality and
neurological sequelae in survivors are inevitable. We investigated the effect of combined …

Malaria is a common and sometimes fatal disease caused by infection with Plasmodium
parasites. Cerebral malaria (CM) is a most severe complication of infection with Plasmodium …

Cerebral malaria (CM) is the severe neurological complication associated with Plasmodium
falciparum infection. In clinical settings CM is predominantly characterized by fever, epileptic …

Malaria infections due to the Plasmodium parasite remains a major global health problem.
Plasmodium falciparum is responsible for majority of the severe cases, resulting in more …

In this chapter we will critically review the body of evidence indicating that host immune
responses to parasitic infection also play a critical role in cerebral malaria pathogenesis, in …