The GATA family of transcription factors is of crucial importance during embryonic
development, playing complex and widespread roles in cell fate decisions and tissue …

Congenital heart disease (CHD) is the most common human birth defect and remains a
leading cause of mortality in childhood. Although advances in clinical management have …

Congenital heart defects (CHD) include structural abnormalities of the heart or/and great
vessels that are present at birth. CHD affects around 1% of all newborns worldwide …

Congenital heart disease (CHD), the most common form of developmental abnormality in
humans, remains a leading cause of morbidity and mortality in neonates. Genetic defects …

These new insights into the genetic contributors of AVD have offered new avenues for
translational disease investigation, bridging molecular discoveries to emergent …

Congenital cardiovascular malformations represent the most common type of birth defect
and encompass a spectrum of anomalies that range from mild to severe. The etiology of …

Background Congenital diaphragmatic hernia (CDH) is characterized by a defective closure
of the diaphragm occurring as an isolated defect in 60% of cases. Lung size, liver herniation …

Congenital heart disease (CHD) is the most common type of developmental abnormality in
humans, and is a leading cause for substantially increased morbidity and mortality in …

TBX5, a member of the T-box family of transcription factors, is a dosage sensitive regulator of
heart development. Mutations in TBX5 are responsible for Holt-Oram Syndrome, an …

Congenital heart disease is the leading cause of death in the first year of life. Mutations only
in few genes have been linked to some cases of CHD. Thalidomide was used by pregnant …