Tumor-associated macrophages are an abundant cell type in the tumor microenvironment.
These macrophages serve as a promising target for treatment of cancer due to their roles in …

The fine equilibrium of bone homeostasis is maintained by bone-forming osteoblasts and
bone-resorbing osteoclasts. Here, we show that TAM receptors MERTK and TYRO3 exert …

Intracerebral hemorrhage (ICH) is a common neurological disease, causing severe disability
and even deaths. Stem cell transplantation has been increasingly used in stroke therapy …

Systemic sclerosis (SSc) is a connective tissue disorder characterized by microvascular
injury, extracellular matrix deposition, autoimmunity, inflammation, and fibrosis. The clinical …

Apoptotic cell clearance results in the release of growth factors and the action of signaling
molecules involved in tissue homeostasis maintenance. Here, we investigated whether and …

Long-term inhalation of crystalline silica particles leads to silicosis characterized by
pulmonary inflammation and interstitial fibrosis. The growth arrest-specific protein 6 (Gas6) …

Objectives: Alveolar macrophage polarization and role on alveolar repair during human
acute respiratory distress syndrome remain unclear. This study aimed to determine during …

Transplantation of neural stem cells (NSCs) is a potential strategy for the treatment of spinal
cord transection (SCT). Here we investigated whether transplanted NSCs would improve …

The epithelial-mesenchymal transition (EMT) is important in organ fibrosis. We hypothesized
that growth arrest-specific protein 6 (Gas6) and its underlying mechanisms play roles in the …

The epithelial-mesenchymal transition (EMT) and fibroblast activation are major events in
idiopathic pulmonary fibrosis pathogenesis. Here, we investigated whether growth arrest …