Poor microenvironmental conditions are a characteristic feature of solid tumors. Such
conditions occur because the tumor vascular supply, which develops from the normal host …

Knowledge about the oxygenation of human tumors and its importance in the response to
radiotherapy is crucial to the effort to develop improved treatment methods for radiotherapy …

Background and purpose: Hypoxic tumor cells are known to be relatively radioresistant. The
aim of the study was to correlate oxygenation status and radiation response in advanced …

It is now well established that most animal solid tumors contain oxygen-deficient hypoxic
cells and that these cells will influence the response of those tumors to radiation. Identifying …

Purpose: To investigate the relationship between tumor oxygenation and the blood
hemoglobin (Hb) concentration in patients with squamous cell carcinoma of the head and …

Tumour oxygenation status was measured by a polarographic needle electrode in 31
patients with lymph node metastasis of squamous cell carcinoma of the head and neck and …

We have previously demonstrated in primary cancer of the uterine cervix that tumor hypoxia,
as determined polarographically, is strongly associated with clinical malignant progression …

Tumor cells at low oxygen tension are relatively radioresistant. The hypoxic fraction of
individual tumors before, during and after radiotherapy is likely to have prognostic value but …

Introduction. Hypoxia induced radioresistance has been acknowledged for decades. One of
the indirect evidences of the influence of hypoxia on radiation response comes from the …

BACKGROUND AND PURPOSE: Hypoxia adversely affects treatment outcome in human
uterine cervical cancer. Here, we present the results of a prospective international multi …