Coenzyme Q biochemistry and biosynthesis

RM Guerra, DJ Pagliarini - Trends in biochemical sciences, 2023 - cell.com
Coenzyme Q (CoQ) is a remarkably hydrophobic, redox-active lipid that empowers diverse
cellular processes. Although most known for shuttling electrons between mitochondrial …

Disorders of human coenzyme Q10 metabolism: an overview

I Hargreaves, RA Heaton, D Mantle - International journal of molecular …, 2020 - mdpi.com
Coenzyme Q10 (CoQ10) has a number of vital functions in all cells, both mitochondrial and
extramitochondrial. In addition to its key role in mitochondrial oxidative phosphorylation …

Biochemistry of mitochondrial coenzyme Q biosynthesis

JA Stefely, DJ Pagliarini - Trends in biochemical sciences, 2017 - cell.com
Coenzyme Q (CoQ, ubiquinone) is a redox-active lipid produced across all domains of life
that functions in electron transport and oxidative phosphorylation and whose deficiency …

Mitochondrial protein interaction mapping identifies regulators of respiratory chain function

BJ Floyd, EM Wilkerson, MT Veling, CE Minogue, C Xia… - Molecular cell, 2016 - cell.com
Mitochondria are essential for numerous cellular processes, yet hundreds of their proteins
lack robust functional annotation. To reveal functions for these proteins (termed MXPs), we …

[HTML][HTML] Coenzyme Q biosynthesis in health and disease

MJ Acosta, LV Fonseca, MA Desbats, C Cerqua… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Coenzyme Q (CoQ, or ubiquinone) is a remarkable lipid that plays an essential role in
mitochondria as an electron shuttle between complexes I and II of the respiratory chain, and …

The mitochondrial coenzyme Q junction and complex III: Biochemistry and pathophysiology

R Banerjee, J Purhonen, J Kallijärvi - The FEBS journal, 2022 - Wiley Online Library
Coenzyme Q (CoQ, ubiquinone) is the electron‐carrying lipid in the mitochondrial electron
transport system (ETS). In mammals, it serves as the electron acceptor for nine mitochondrial …

Coenzyme Q10 deficiencies: pathways in yeast and humans

AM Awad, MC Bradley… - Essays in …, 2018 - portlandpress.com
Coenzyme Q (ubiquinone or CoQ) is an essential lipid that plays a role in mitochondrial
respiratory electron transport and serves as an important antioxidant. In human and yeast …

[HTML][HTML] Coenzyme Q biosynthesis and its role in the respiratory chain structure

M Alcázar-Fabra, P Navas, G Brea-Calvo - Biochimica et Biophysica Acta …, 2016 - Elsevier
Coenzyme Q (CoQ) is a unique electron carrier in the mitochondrial respiratory chain, which
is synthesized on-site by a nuclear encoded multiprotein complex. CoQ receives electrons …

Primary coenzyme Q10 deficiency: an update

D Mantle, L Millichap, J Castro-Marrero, IP Hargreaves - Antioxidants, 2023 - mdpi.com
Coenzyme Q10 (CoQ10) has a number of vital functions in all cells, both mitochondrial and
extra-mitochondrial. In addition to its key role in mitochondrial oxidative phosphorylation …

Metabolic targets of coenzyme Q10 in mitochondria

A Hidalgo-Gutiérrez, P González-García… - Antioxidants, 2021 - mdpi.com
Coenzyme Q10 (CoQ10) is classically viewed as an important endogenous antioxidant and
key component of the mitochondrial respiratory chain. For this second function, CoQ …